8 Best Ketamine Clinics in Chicago (2026) — Verified & Reviewed

• By Healing Maps Editorial Staff
• September 8, 2022June 2, 2026
• Ketamine Articles ketamine therapy ketamine treatment
• With 0 comments

Chicago is one of the most active ketamine demand markets in the Midwest. Cook County — home to 5.22 million residents with a 18.7% adult depression prevalence — anchors a mature clinical market with growing Spravato access. More than 50 Illinois residents have recently contacted HealingMaps seeking a ketamine clinic. This guide is the shortlist we send them.

Chicago Ketamine Market Snapshot

Sources: CDC PLACES 2023 (Cook County, IL, crude prevalence) · U.S. Census ACS 5 Year · HealingMaps proprietary patient inquiry data.

• Adult depression in Cook County, IL: 18.7%
• Frequent mental distress (14+ days per month): 16.2%
• Adults lacking health insurance: 11.8%
• Short sleep duration (under 7 hours): 38.7%
• Chicago-area population: 5,225,367 · median household income $78,304
• Recent Chicago-area inquiries to HealingMaps: More than 50 Illinois residents have recently contacted us seeking ketamine care

Behind this data: HealingMaps has analyzed 23,496 patient inquiries (Oct 2022 – Mar 2026), mapped 1,473 verified clinics across 3,142 counties, scraped 132 clinic pricing pages, and collected 658 practitioner survey responses. This snapshot reflects our multi-source methodology.

What this means for you: Chicago operates as a mature ketamine market with both cash-pay and Spravato-insured pathways. Ask every clinic about Spravato REMS certification, FSA/HSA eligibility, and therapy integration support before booking.

Chicago, Illinois Ketamine Treatment Cost Calculator

8 Best Ketamine Clinics in Chicago: How We Chose Which Clinics Make the List

Our editorial team evaluated each clinic based on provider credentials, Google and Yelp reviews, treatment options, pricing transparency, and patient experience. We verify that every clinic listed is currently operating and accepting new patients. Clinics that have closed — including Field Trip Health Chicago — have been removed.

The Best Ketamine Clinics in Chicago

1. Hopemark Health Oak Brook (Formerly Wesana Clinics)

Known For: Chicagoland’s largest ketamine program with 4,000+ treatments and two locations (Oak Brook + downtown Chicago)

Why We Picked Them: Hopemark Health — formerly Wesana Clinics and Advanced Psychiatric Solutions — has the deepest ketamine experience in the Chicago metro. Their psychiatrist-led model combines IV infusions with therapy integration, dTMS, and EMDR under one roof.

The Oak Brook flagship has been a pioneer in the region since its early days as one of the first dedicated ketamine clinics in the western suburbs. Dr. Nazeer’s team offers a comprehensive psychiatric approach rather than standalone infusions, making it a strong fit for patients who want multi-modal treatment.

“Dr. Nazeer and his team truly saved my life. After years of treatment-resistant depression, the ketamine program here gave me hope again. The staff is compassionate and professional.” — Google Review

2. MD Infusions

Known For: Near-perfect Google reviews (4.9 stars) and specialized chronic pain protocols on Chicago’s North Shore

Why We Picked Them: MD Infusions stands out for its physician-led approach rooted in anesthesiology — giving them particular expertise in pain-related ketamine protocols. Their 4.9-star Google rating reflects consistently positive patient experiences.

Located in Northbrook on Chicago’s North Shore, MD Infusions serves patients across the northern suburbs. Their anesthesiology background makes them especially skilled at dosing and monitoring, and they treat both mood disorders and chronic pain conditions including CRPS and fibromyalgia.

“The entire experience was professional and caring. I’ve seen significant improvement in my depression after just three sessions. The medical staff made me feel safe the entire time.” — Google Review

3. Renew Ketamine & Wellness Center

Known For: ER physician-led infusion center in downtown Naperville with strong patient satisfaction scores

Why We Picked Them: Renew Ketamine brings emergency medicine expertise to ketamine therapy — Dr. Mansour’s ER background means advanced monitoring and dosing precision. Their downtown Naperville location fills a gap in the western suburbs.

Located above Hugo’s Frog Bar in the heart of downtown Naperville, Renew Ketamine offers a comfortable setting with ample parking. Beyond ketamine, they provide NAD+ and wellness IV infusions. Their ER physician-led model prioritizes safety and clinical rigor during every session.

“Five stars all around. The team is compassionate, empathetic, and really makes you feel seen and valued. The treatment created a shift within me that I honestly did not expect.” — Google Review

4. Imagine Healthcare

Known For: Chicago’s first woman-owned ketamine clinic, led by a palliative care physician with deep expertise in end-of-life and existential distress

Why We Picked Them: Imagine Healthcare brings a unique palliative care perspective to ketamine therapy. Dr. Norris’s background in end-of-life medicine adds a layer of compassion and expertise that few ketamine clinics can match, and their KAP integration sets them apart.

Situated in the Streeterville neighborhood on Lake Shore Drive, Imagine Healthcare offers a boutique experience in a premium location. Their focus on ketamine-assisted psychotherapy — not just standalone infusions — makes them ideal for patients seeking deeper therapeutic integration alongside their ketamine treatment.

“Imagine Healthcare is the real deal. Dr. Norris and her team create a warm, safe space. The combination of therapy and ketamine was transformative for my anxiety and depression.” — Google Review

5. Lott Behavioral Health

Known For: Most affordable IV ketamine in the Chicago metro at $350/infusion, with transparent pricing and Spravato coverage

Why We Picked Them: Lott Behavioral Health offers the best value in the Chicago area — $350 per infusion is well below the regional average. Their combination of IV ketamine, IM ketamine, and insurance-covered Spravato gives patients multiple treatment pathways.

Located in the western suburbs near Lisle and Warrenville, Lott Behavioral Health has built a loyal patient base over six-plus years. Dr. Lott’s psychiatric training ensures patients receive thorough mental health evaluations before starting ketamine, and the clinic’s smaller size means more personalized attention.

“Dr. Lott is amazing. He takes the time to understand your situation and explains everything clearly. The ketamine treatments have been life-changing for my treatment-resistant depression.” — Google Review

6. Ketamine Center of Chicago

Known For: Chicago’s longest-tenured and highest-volume ketamine practice — 15,000+ infusions since 2017 under anesthesiologist Dr. Bal Nandra, with a proprietary RECOVER-IV addiction program and Stellate Ganglion Block for PTSD.

Why We Picked Them: Ketamine Center of Chicago (operating as IV Solution & Ketamine Centers) is the most experienced ketamine clinic in Chicagoland by a wide margin. Dr. Nandra’s anesthesiology background plus the 15,000+ session count gives clinician depth uncommon in the standalone-ketamine-clinic format. The RECOVER-IV addiction program is a proprietary protocol distinct from anything else in the Chicago market.

Beyond IV ketamine, the clinic offers IM ketamine, Spravato, Stellate Ganglion Block (SGB) for PTSD, and NAD+ therapy. Integration coaching is available alongside ketamine dosing for patients who want structured therapy support. The West Loop and Lincoln Park locations cover central Chicago.

“Dr. Nandra and the team have administered thousands of infusions — you feel it from the moment you walk in. Their experience showed in everything from the dosing decisions to the recovery environment.” — Patient testimonial

7. Relief Mental Health (West Loop)

Known For: Multi-location Chicago mental health practice combining IV ketamine + Spravato + TMS + psychiatry + therapy under one roof. West Loop and Lakeview locations.

Why We Picked Them: Relief Mental Health is one of the few Chicago-area practices integrating ketamine + Spravato + TMS + medication management + talk therapy on one clinical team. The full-stack mental health model means patients can stay with one practice through escalation rather than coordinating between separate infusion clinics, TMS centers, and psychiatrists.

The West Loop location at 815 W Van Buren anchors the central Chicago presence; the Lakeview sister clinic extends north-side coverage. Eight clinical providers (1 MD, 3 NP/PA, 4 therapists) support the practice. Spravato follows the FDA-required two-hour observation window; TMS runs the standard 36-session course.

“Having my Spravato sessions, TMS course, and therapy all coordinated at one practice removed a ton of friction from getting better. Relief was the right fit for how I needed care delivered.” — Patient testimonial

8. Stella Mental Health (Westmont)

Known For: Western-suburbs anchor of the national Stella Mental Health network — multi-modality (Spravato + Deep TMS + Stellate Ganglion Block + ketamine) under one practice, covering DuPage County.

Why We Picked Them: Stella’s combination of Deep TMS (BrainsWay) plus Spravato plus Stellate Ganglion Block (the dual-sympathetic-reset protocol for PTSD) under one practice is the deepest interventional-psychiatry stack in the Chicago suburbs. The national Stella brand provides protocol standardization across locations — useful for patients who relocate or want consistency with other markets.

The Westmont location sits in the DuPage County / I-88 corridor, covering western suburbs (Oak Brook, Naperville, Hinsdale, Downers Grove) that would otherwise require driving into central Chicago. Stella’s multimodality model emphasizes layering interventional protocols based on response — patients often progress through ketamine → Spravato → TMS → SGB depending on what produces durable relief.

“Westmont was the right Stella location for me — closer than driving into the city, and the Deep TMS plus Spravato combination is what finally worked after years of failed antidepressants.” — Patient testimonial

Best Ketamine Clinics in Chicago — In Conclusion

Chicago’s ketamine therapy landscape spans from the Loop to the western suburbs, with options ranging from comprehensive psychiatric programs to focused infusion clinics. Hopemark Health Oak Brook leads with the most experience (4,000+ treatments), while MD Infusions earns the highest patient ratings. Lott Behavioral Health offers the best pricing at $350 per infusion, and Imagine Healthcare provides the deepest therapy integration. We recommend contacting two to three clinics for consultations to find the best fit for your needs.