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✓ Last verified: April 7, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff
Known For: 30+ combined years of emergency medicine experience from co-founders Dr. Jonathan Leake and Keith Parris, ACNP-BC — bringing acute care precision to ketamine and IV therapy.
| Review Scores | Yelp: 34 reviews — praised for professional staff and relaxing atmosphere |
| Location | Charlotte, NC (Dilworth) |
| Address | 228 E Blvd, Suite 200, Charlotte, NC 28203 |
| Phone | (980) 352-0042 |
| Website | charlotte.hydratemedical.com |
| Treatments | IV Ketamine Infusions, IV Hydration Therapy |
| Conditions Treated | Severe Depression, Anxiety, PTSD, Chronic Pain |
| Cost | Contact for ketamine pricing |
| Insurance | Contact for details |
| KAP Available? | No |
| Clinical Lead | Dr. Jonathan Leake, MD & Keith Parris, ACNP-BC (30+ yrs emergency medicine) |
HealingMaps Take: Hydrate Medical brings over 30 combined years of emergency medicine experience to their ketamine practice. Co-founders Dr. Leake and Keith Parris have witnessed the powerful healing effects of ketamine firsthand, and their emergency-trained RNs ensure every session is monitored with acute care precision.
Market Position: Hydrate Medical is an IV-ketamine-focused clinic in the Charlotte metro — the most common cash-pay protocol in the HealingMaps verified directory.
Is Hydrate Medical Right for You?
✓ Choose Hydrate Medical if:
- You want supervised IV ketamine with real-time medical monitoring
- You’re treating co-occurring depression and PTSD
✗ Look elsewhere if:
- You need Spravato (FDA-approved esketamine) covered by your insurance
- You want ketamine-assisted psychotherapy (KAP) with integrated talk therapy
Hydrate Medical Ketamine Cost Calculator
How Much Will Ketamine Therapy Cost?
Estimate your out-of-pocket range based on patient-reported pricing and HealingMaps proprietary clinic data.
Estimated per session
$525–$900
Range: $450–$1,500/session
Estimated total program
$3,150–$5,400
Range: $2,700–$9,000/6-session series
Select a treatment type to see pricing context.
Ketamine Protocols Compared — What’s Offered at Hydrate Medical
Industry pricing reference. Hydrate Medical has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.
| Protocol | Typical Industry Cost | Offered Here |
|---|---|---|
| IV Ketamine | $350–$650/session | ✓ Yes |
| Spravato (esketamine) | $0–$250 copay (insured) | — |
| IM Ketamine | $250–$400/injection | — |
| KAP (with therapist) | $400–$1,200/session | — |
| At-home troches | $150–$300/month | — |
What to Expect at Your First Hydrate Medical Appointment
- Initial intake call — Brief medical history review, depression and anxiety screening, and medical clearance for IV ketamine. Call (980) 352-0042 to schedule.
- Medical evaluation — in-person or telehealth psychiatric assessment, vitals check, and review of current medications with the Hydrate Medical clinical team.
- First treatment session — supervised IV ketamine infusion in a private treatment room, lasting approximately 60–90 minutes (40-minute infusion + recovery). Sessions are held at 228 E Blvd, Suite 200, Charlotte, NC 28203. You’ll have a comfortable chair or recliner, dim lighting, and direct medical monitoring throughout.
- Recovery and follow-up — observation period after dosing, mood check-in with the clinical team, and scheduling your next session. Arrange for a ride home; do not drive for 24 hours after your IV session.
What to Ask on Your Hydrate Medical Consult Call
- How long has the Hydrate Medical clinical team been delivering ketamine therapy, and what specialty training do your providers hold?
- Does Hydrate Medical provide a superbill for out-of-network insurance reimbursement, and what’s a typical 6-session total cost including any follow-up?
- What does Hydrate Medical recommend for patients who don’t respond to the standard 6-session acute series?
Charlotte Ketamine Market Snapshot
Sources: CDC PLACES 2023 (Mecklenburg County, NC, crude prevalence) · U.S. Census ACS 5 Year · HealingMaps proprietary patient inquiry data.
- Adult depression in Mecklenburg County, NC: 22.4%
- Frequent mental distress (14+ days per month): 15.7%
- Adults lacking health insurance: 10.1%
- Mecklenburg County population: 1,115,403 · median household income $79,265
- Recent Charlotte-area inquiries to HealingMaps: A growing stream of North Carolina residents have recently contacted us seeking ketamine care
Behind this data: HealingMaps has analyzed 23,496 patient inquiries (Oct 2022 – Mar 2026), mapped 1,473 verified clinics across 3,142 counties, scraped 132 clinic pricing pages, and collected 658 practitioner survey responses. This snapshot reflects our multi-source methodology.
From the 2026 Ketamine Industry Report
The U.S. ketamine therapy market is $3.4 billion today and projected to reach $6.9 billion by 2030 — more than doubling in a six-year window as access and awareness expand. Source: HealingMaps 2026 Ketamine Clinic Intelligence Report — drawn from 23,496 patient inquiries and 132 clinic website analyses.
Patient Questions about Hydrate Medical
This 4-question summary is matched to the protocols and conditions Hydrate Medical treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.
Is Hydrate Medical suited for treatment-resistant depression?
Hydrate Medical treats depression via IV ketamine (off-label, evidence-based). Insurance coverage is rare for IV/KAP — most patients pay out of pocket. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.
Does Hydrate Medical treat chronic pain conditions?
Yes — Hydrate Medical treats chronic pain. They use IV ketamine for pain, which typically means longer infusion times and higher cumulative doses than mental-health protocols. Common indications include complex regional pain syndrome (CRPS), fibromyalgia, and certain neuropathic pain syndromes. Pain pricing varies significantly by structure: per-infusion vs. multi-day inpatient packages — verify how this clinic structures their billing.
Does Hydrate Medical treat PTSD?
Yes — Hydrate Medical treats PTSD. Ketamine for trauma differs from depression treatment: dosing is often lower per session, and pairing the protocol with trauma-focused therapy between sessions is common. A reasonable consult question: whether PTSD patients here typically use ketamine alone or alongside an outside therapist.
Can Hydrate Medical help with anxiety disorders?
Yes — Hydrate Medical treats anxiety, including generalized anxiety, social anxiety, and panic disorder. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines. Worth asking which of their protocols they typically recommend for anxiety-primary patients.
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Healing Maps Editorial Staff
View all posts by Healing Maps Editorial StaffThe Healing Maps Editorial Team has decades of experience across all facets of the psychedelic industry. From assessing studies and clinic research, to working with clinician's and clinics, we help provide data-backed information to psychedelic-curious individuals across the globe.
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