Kai MacDonald Ketamine Clinic – San Diego, California Ketamine Clinics

By Healing Maps Editorial Staff
April 8, 2022May 12, 2026
ketamine therapy ketamine treatment psychiatrist
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3368 2nd Avenue, Suite B San Diego, California

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✓ Last verified: February 17, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff

Known For: Dr. Kai MacDonald’s concierge psychiatry practice in San Diego offers intimate, personalized ketamine therapy as part of a whole-person treatment approach. Named one of San Diego Magazine’s Top Doctors from 2009–2013, Dr. MacDonald takes a holistic perspective that includes lifestyle, diet, and individualized treatment planning alongside ketamine. Operating outside the insurance-based model allows for extended time with each patient and deeper therapeutic relationships.

Google Reviews	⭐ Highly rated concierge practice
Location	San Diego, California
Address	3368 2nd Avenue, Suite B, San Diego, CA
Phone	(619) 203-7393
Website	kaimacdonald.com
Treatments Offered	Ketamine Therapy, Concierge Psychiatry, Medication Management, Holistic Treatment Planning
Conditions Treated	Mood Disorders, Anxiety Disorders, PTSD, Attention Disorders, Addiction, Substance Abuse
Cost	$300–$500 per session depending on condition severity
Insurance Accepted	Concierge model — self-pay; not insurance-based
KAP Available	Yes — psychiatric ketamine therapy with holistic integration
Clinical Lead	Dr. Kai MacDonald, MD (Board-Certified Psychiatrist)

HealingMaps Take: Dr. Kai MacDonald’s practice represents the gold standard of personalized ketamine care in San Diego. As a board-certified psychiatrist recognized among San Diego’s top doctors, he brings deep clinical expertise to every treatment plan. The concierge model means more face time and individualized attention than typical high-volume clinics can offer, though it does come at a higher out-of-pocket cost since insurance isn’t accepted. For patients who prioritize a deep doctor-patient relationship and a holistic approach to ketamine therapy, this is one of San Diego’s premier options.

Market Position: Kai MacDonald Ketamine Clinic is a verified ketamine provider in the metro on HealingMaps — one of 1,473 clinics we have mapped and tracked across 3,142 U.S. counties.

Is Kai MacDonald Ketamine Clinic Right for You?

✓ Choose Kai MacDonald Ketamine Clinic if:

You’re seeking ketamine-assisted psychotherapy (KAP) with a licensed therapist alongside dosing

✗ Look elsewhere if:

You’re seeking ketamine for chronic pain (this clinic focuses on mental health)

Kai MacDonald Ketamine Clinic Ketamine Cost Calculator

How Much Will Ketamine Therapy Cost?

Estimate your out-of-pocket range based on patient-reported pricing and HealingMaps proprietary clinic data.

Treatment type

Sessions planned

Insurance

Estimated per session

$525–$900

Range: $450–$1,500/session

Estimated total program

$3,150–$5,400

Range: $2,700–$9,000/6-session series

Your estimate vs. national patient-reported median Based on national tracking, adjusted for Manhattan, NY market

Select a treatment type to see pricing context.

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A HealingMaps specialist will follow up within one business day with providers that match your estimate, protocol, and insurance situation.

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Ketamine Protocols Compared — What’s Offered at Kai MacDonald Ketamine Clinic

Industry pricing reference. Kai MacDonald Ketamine Clinic’s posted price: $300–$500 per session depending on condition severity. Contact the clinic for any package or sliding-scale options. The calculator above shows metro-level cost estimates across protocols.

Protocol	Typical Industry Cost	Offered Here
IV Ketamine	$350–$650/session	—
Spravato (esketamine)	$0–$250 copay (insured)	—
IM Ketamine	$250–$400/injection	—
KAP (with therapist)	$400–$1,200/session	✓ Yes
At-home troches	$150–$300/month	—

What to Expect at Your First Kai MacDonald Ketamine Clinic Appointment

Initial intake call — Medical history review and clinical eligibility check. Call (619) 203-7393 to schedule. Kai MacDonald Ketamine Clinic’s posted pricing: $300–$500 per session depending on condition severity.
Medical evaluation — in-person or telehealth psychiatric assessment, vitals check, and review of current medications with the Kai MacDonald Ketamine Clinic clinical team.
First treatment session — supervised ketamine therapy session in a private treatment room, lasting approximately 60–90 minutes. Sessions are held at 3368 2nd Avenue, Suite B, San Diego, CA. You’ll have a comfortable chair or recliner, dim lighting, and direct medical monitoring throughout.
Recovery and follow-up — observation period after dosing, mood check-in with the clinical team, and scheduling your next session. Arrange for a ride home; do not drive for 24 hours after your ketamine session.

What to Ask on Your Kai MacDonald Ketamine Clinic Consult Call

How long has the Kai MacDonald Ketamine Clinic clinical team been delivering ketamine therapy, and what specialty training do your providers hold?
What’s Kai MacDonald Ketamine Clinic’s typical full-program cost for the integration-therapy bundle, and do you accept HSA/FSA payments?
Is the therapist who guides KAP sessions independently licensed, and how long are integration sessions after the dosing portion?
What does Kai MacDonald Ketamine Clinic recommend for patients who don’t respond to the standard 6-session acute series?

Ketamine Market Snapshot

Sources: CDC PLACES 2023 (, state-level prevalence) · U.S. Census ACS 5 Year · HealingMaps proprietary patient inquiry data.

Adult depression in : N/A
Frequent mental distress (14+ days per month): N/A
Adults lacking health insurance: N/A
Recent -area inquiries to HealingMaps: A growing stream of residents have recently contacted us seeking ketamine care

Behind this data: HealingMaps has analyzed 23,496 patient inquiries (Oct 2022 – Mar 2026), mapped 1,473 verified clinics across 3,142 counties, scraped 132 clinic pricing pages, and collected 658 practitioner survey responses. This snapshot reflects our multi-source methodology.

From the 2026 Ketamine Industry Report

Depression is the #1 condition cited in 20.9% of HealingMaps ketamine inquiries, followed by PTSD (13.5%) and anxiety (11.4%) — the three together account for nearly half of all patient demand. Source: HealingMaps 2026 Ketamine Clinic Intelligence Report — drawn from 23,496 patient inquiries and 132 clinic website analyses.

Patient Review

“Dr. MacDonald takes the time to truly understand each patient as a whole person. His approach to ketamine therapy goes far beyond just the treatment itself — he considers lifestyle, diet, and everything that contributes to mental wellness.” — Kai MacDonald Ketamine Clinic patient

Known For: Concierge psychiatrist with 25+ years experience offering deeply personal KAP with attachment-based and emotion-focused therapy

Review Scores	Yelp: 15 reviews · Healthgrades: Outstanding · WebMD: Highly recommended
Location	San Diego (Hillcrest), California
Address	3368 2nd Avenue, Suite B, San Diego, CA 92103
Phone	(619) 203-7393
Website	kaimacdonald.com
Treatments	Ketamine-Assisted Psychotherapy, Concierge Psychiatry, Medication Management
Conditions Treated	Depression, Anxiety, PTSD, Trauma, Addiction, Mood Disorders
Cost	$300–$500 per session (concierge model)
Insurance	Not insurance-based — concierge practice
KAP Available?	Yes — advanced training in attachment-based and emotion-focused KAP
Clinical Lead	Dr. Kaimana MacDonald, MD — Psychiatrist, 25+ years, UCSD-affiliated

HealingMaps Take: Dr. MacDonald is one of the most respected ketamine providers in San Diego. His concierge model means longer appointments, deeper therapeutic relationships, and a dual expertise in both psychiatry and psychotherapy. Reviews across every platform are exceptional. For patients wanting a physician-led KAP experience, this is a top pick.

Patient Review

“Through Dr. MacDonald’s treatment that combines medicine, psychiatry, and emotional strengthening, I found a balance that greatly improved my quality of life.” — WebMD Review (7-year patient)

Offering “concierge psychiatry,” the Kai MacDonald Ketamine Clinic in San Diego, California provides intimate psychiatric and ketamine therapy treatments.

As a clinic separated from the insurance-based model, Dr. MacDonald’s practice allows for more time with each patient, which builds a personal relationship between client and doctor.

Although ketamine plays a large role in many patients’ treatments, the Kai MacDonald Ketamine Clinic also focuses on “whole-person treatment,” including such aspects as lifestyle and diet. It is Dr. MacDonald’s belief that, by treating patients from this holistic perspective, each patient will receive an individualized treatment plan that takes into account all aspects of a patient’s health, rather than simply focusing on the difficult to manage mental health aspects.

Dr. Kai MacDonald first became aware of the remarkable potential for ketamine use in psychiatry when he “supervised IV administration of ketamine to a person with severe depression” in 2013. Although he has been aware of the utility of ketamine in treating resistant conditions, Dr. MacDonald chose to wait for further research and protocols to be developed before he offered the treatment to his clients.

Individuals whose struggles with depression have not been alleviated by mainstream medications will find that ketamine infusion therapy at the Kai MacDonald Ketamine Clinic offers an potential route to healing and hope.

Offered Treatments

Intramuscular Ketamine Injections
Sublingual Ketamine lozenges

Treated Conditions

Attention Disorders
Mood Disorders
Anxiety Disorders
Trauma-based Disorders
Substance Abuse

Important Info

Individual treatments cost between $300 – $500, depending on the severity of the condition.
Please contact the clinic for more information about payment and insurance.
Contact the clinic for further information about possible contraindicative conditions or medications.

Your Treatment: What to Expect

Once ketamine has been determined to be a suitable medication for your condition, the initial treatment takes place at Dr. MacDonald’s clinic.

Throughout the process, patients are monitored, as some people report dissociative sensations, such as floating, during treatment. Such side effects are completely normal, and fade soon after the treatment ends.

Who is this treatment for?

Treatments at the Kai MacDonald Ketamine Clinic are for individuals who are struggling with the symptoms of difficult to manage mental health conditions. While many people respond well to mainstream oral medications, a significant portion of sufferers do not.

In laboratory settings, ketamine has shown a 70-75 percent effectiveness in treating these difficult conditions. For those who are seeking further assistance in managing their health, the Kai MacDonald Ketamine Clinic stands ready to help.

Website: https://www.kaimacdonald.com/

Discover more California Ketamine Clinics

Patient Questions about Kai MacDonald Ketamine Clinic

This 2-question summary is matched to the protocols and conditions Kai MacDonald Ketamine Clinic treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.

Does Kai MacDonald Ketamine Clinic offer ketamine-assisted psychotherapy (KAP)?

Yes — Kai MacDonald Ketamine Clinic offers KAP, which combines ketamine dosing with structured psychotherapy during the dissociative window. KAP sessions are longer than standalone infusions and priced accordingly. A reasonable consult question: whether KAP is delivered by a single integrated provider, or by a separate therapist working with the prescribing clinician.

Can Kai MacDonald Ketamine Clinic help with anxiety disorders?

Yes — Kai MacDonald Ketamine Clinic treats anxiety, including generalized anxiety, social anxiety, and panic disorder. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines. Worth asking which of their protocols they typically recommend for anxiety-primary patients.

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Healing Maps Editorial Staff

View all posts by Healing Maps Editorial Staff

The Healing Maps Editorial Team has decades of experience across all facets of the psychedelic industry. From assessing studies and clinic research, to working with clinician's and clinics, we help provide data-backed information to psychedelic-curious individuals across the globe.

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Kai MacDonald Ketamine Clinic – San Diego, California Ketamine Clinics