✓ Last verified: March 29, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff

Known For: Retreat-style ketamine therapy center nestled in the natural beauty of Topanga Canyon, combining psychedelic-assisted healing with a strong emphasis on integration work and holistic wellness outside of sessions.
| Google Reviews | N/A |
| Location | Topanga Canyon, CA (Greater Los Angeles) |
| Address | Topanga Canyon, CA (exact address provided upon booking) |
| Phone | 866-767-4325 |
| Website | sos.institute (no longer available) |
| Treatments | Ketamine Therapy, Psychedelic Retreats, Integration Coaching |
| Conditions | Depression, Anxiety, PTSD, Personal Growth & Transformation |
| Cost | Contact for pricing (application required) |
| Insurance | Contact clinic for details |
| KAP Available? | Yes – retreat-style with integration coaching |
| Clinical Lead | Clinical Team (apply via website for details) |
HealingMaps Take: The Sense of Self Institute offers a distinctly different ketamine experience from typical clinic settings. Located in the serene natural surroundings of Topanga Canyon, this retreat-style center emphasizes deep personal transformation through ketamine therapy paired with ongoing integration work. The application-based intake process suggests a curated, personalized approach rather than a one-size-fits-all model. The emphasis on doing meaningful work outside of sessions reflects an understanding that lasting healing extends beyond the treatment room. Ideal for patients seeking an immersive, nature-connected psychedelic therapy experience — though the canyon location may require personal transportation.
Market Position: Sense of Self Institute Topanga Canyon treats both depression and PTSD — the two most common ketamine therapy indications, accounting for 34% of HealingMaps patient inquiries.
Industry pricing reference. Sense of Self Institute Topanga Canyon has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.
| Protocol | Typical Industry Cost | Offered Here |
|---|---|---|
| IV Ketamine | $350–$650/session | — |
| Spravato (esketamine) | $0–$250 copay (insured) | — |
| IM Ketamine | $250–$400/injection | — |
| KAP (with therapist) | $400–$1,200/session | ✓ Yes |
| At-home troches | $150–$300/month | — |
This question is matched to the conditions Sense of Self Institute Topanga Canyon treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.
Yes — Sense of Self Institute Topanga Canyon treats PTSD. Ketamine for trauma differs from depression treatment: dosing is often lower per session, and pairing the protocol with trauma-focused therapy between sessions is common. A reasonable consult question: whether PTSD patients here typically use ketamine alone or alongside an outside therapist.
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