Ketamine Research Institute – Sarasota, Florida Ketamine Clinics

✓ Last verified: March 13, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff

Known For: The Ketamine Research Institute in Sarasota is a pioneering ketamine clinic led by Dr. Gerald W. Grass, MD, a former Assistant Professor of Anesthesiology and Pain Medicine at Yale University. The institute developed the RESTORE Ultra-Rapid Ketamine Infusion protocol and offers genetically customized treatments using Genomind Assay testing. They also operate a clinician training program (Mini-Fellowship) that has trained providers nationwide.

HealingMaps Take: The Ketamine Research Institute brings academic-level expertise to clinical practice. Dr. Grass’s Yale background and the proprietary RESTORE protocol set this clinic apart, as does their use of pharmacogenomic testing to customize infusion parameters. The institute’s clinician training program — which reports 70-75% success rates among graduates — further validates their methodology. A strong choice for patients seeking a research-informed approach to ketamine therapy.

Market Position: Ketamine Research Institute is an IV-ketamine-focused clinic in the Sarasota metro — the most common cash-pay protocol in the HealingMaps verified directory.

Ketamine Research Institute Ketamine Cost Calculator

Ketamine Protocols Compared — What’s Offered at Ketamine Research Institute

Industry pricing reference. Ketamine Research Institute has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.

What to Expect at Your First Ketamine Research Institute Appointment

1. Initial intake call — Brief medical history review, depression and anxiety screening, and medical clearance for IV ketamine. Call (800) 850-6979 to schedule.
2. Medical evaluation — in-person or telehealth psychiatric assessment, vitals check, and review of current medications with the Ketamine Research Institute clinical team.
3. First treatment session — supervised IV ketamine infusion in a private treatment room, lasting approximately 60–90 minutes (40-minute infusion + recovery). Sessions are held at 5741 Bee Ridge Rd, Suite 560, Sarasota, FL 34233. You’ll have a comfortable chair or recliner, dim lighting, and direct medical monitoring throughout.
4. Recovery and follow-up — observation period after dosing, mood check-in with the clinical team, and scheduling your next session. Arrange for a ride home; do not drive for 24 hours after your IV session.

What to Ask on Your Ketamine Research Institute Consult Call

• How long has the Ketamine Research Institute clinical team been delivering ketamine therapy, and what specialty training do your providers hold?
• Does Ketamine Research Institute provide a superbill for out-of-network insurance reimbursement, and what’s a typical 6-session total cost including any follow-up?
• Are you set up for both commercial insurance Spravato pathways and cash-pay IV ketamine, or primarily one?
• Does Ketamine Research Institute require a referral from a current treating psychiatrist, and how do you handle outside-prescriber medication-management coordination?
• What does Ketamine Research Institute recommend for patients who don’t respond to the standard 6-session acute series?

Patient Questions about Ketamine Research Institute

This 4-question summary is matched to the protocols and conditions Ketamine Research Institute treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.

Is Ketamine Research Institute suited for treatment-resistant depression?

Ketamine Research Institute treats depression via IV ketamine (off-label, evidence-based). Insurance coverage is rare for IV/KAP — most patients pay out of pocket. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.

Does Ketamine Research Institute treat chronic pain conditions?

Yes — Ketamine Research Institute treats chronic pain. They use IV ketamine for pain, which typically means longer infusion times and higher cumulative doses than mental-health protocols. Common indications include complex regional pain syndrome (CRPS), fibromyalgia, and certain neuropathic pain syndromes. Pain pricing varies significantly by structure: per-infusion vs. multi-day inpatient packages — verify how this clinic structures their billing.

Does Ketamine Research Institute treat PTSD?

Yes — Ketamine Research Institute treats PTSD. Ketamine for trauma differs from depression treatment: dosing is often lower per session, and pairing the protocol with trauma-focused therapy between sessions is common. A reasonable consult question: whether PTSD patients here typically use ketamine alone or alongside an outside therapist.

Can Ketamine Research Institute help with anxiety disorders?

Yes — Ketamine Research Institute treats anxiety, including generalized anxiety, social anxiety, and panic disorder. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines. Worth asking which of their protocols they typically recommend for anxiety-primary patients.

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Review (1)

• 
  Kelly

  May 19, 2022 at 12:20 am

  I’m interested in receiving ketamine treatment

  Helpful Review