Klarisana – Denver, Colorado Ketamine Clinics

✓ Last verified: February 22, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff

Known For: Klarisana is a pioneering multi-location ketamine therapy provider that has been treating chronic pain and mental health conditions since 2015. The Denver location offers intramuscular (IM) ketamine (Klarisana moved from IV to IM injections in 2020), Spravato, ketamine-assisted psychotherapy (KAP), medication management and talk therapy in a clinical setting focused primarily on severe depression, PTSD, anxiety, and chronic pain. With over 260 reviews and locations across multiple states, Klarisana brings institutional scale and deep clinical experience to each patient encounter.

💡 No clinic-specific pricing posted? See our ketamine therapy cost guide for typical pricing ranges by treatment type and insurance pathways.

HealingMaps Take: Klarisana’s Denver location benefits from the brand’s years of multi-state experience treating thousands of patients since 2015. The 4.0-star rating across 263 reviews reflects a large sample size—more data points than most local competitors—giving prospective patients a realistic picture of outcomes. The availability of standalone IM ketamine sessions, Spravato and full KAP sessions provides flexibility depending on patient needs and budget. As a larger organization, Klarisana brings standardized protocols and clinical infrastructure that smaller practices may lack. A solid choice for patients who value proven systems and high-volume experience.

Market Position: Klarisana treats both depression and PTSD — the two most common ketamine therapy indications, accounting for 34% of HealingMaps patient inquiries.

Klarisana Ketamine Cost Calculator

Ketamine Protocols Compared — What’s Offered at Klarisana

Industry pricing reference. Klarisana has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.

What to Expect at Your First Klarisana Appointment

1. Initial intake call — Medical history review and clinical eligibility check. Call (303) 535-7548 or visit klarisana.com to schedule.
2. Medical evaluation — in-person or telehealth psychiatric assessment, vitals check, and review of current medications with the Klarisana clinical team.
3. First treatment session — supervised ketamine therapy session in a private treatment room, lasting approximately 60–90 minutes. Sessions are held at 1240 South Parker Rd, Suite 100, Denver, CO 80231. You’ll have a comfortable chair or recliner, dim lighting, and direct medical monitoring throughout.
4. Recovery and follow-up — observation period after dosing, mood check-in with the clinical team, and scheduling your next session. Arrange for a ride home; do not drive for 24 hours after your ketamine session.

What to Ask on Your Klarisana Consult Call

• How long has the Klarisana clinical team been delivering ketamine therapy, and what specialty training do your providers hold?
• What’s Klarisana’s typical full-program cost for the integration-therapy bundle, and do you accept HSA/FSA payments?
• Colorado’s Natural Medicine Health Act covers certain psychedelics — how does your ketamine practice integrate with broader psychedelic-therapy options patients may consider?
• Is the therapist who guides KAP sessions independently licensed, and how long are integration sessions after the dosing portion?
• What does Klarisana recommend for patients who don’t respond to the standard 6-session acute series?

Patient Questions about Klarisana

This 5-question summary is matched to the protocols and conditions Klarisana treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.

What ketamine protocols does Klarisana offer?

Klarisana offers IM ketamine, Spravato and KAP. Patients can switch between or combine modalities without changing providers. Confirm specific dosing schedules and which protocols are recommended for your condition during your consult.

Does Klarisana offer ketamine-assisted psychotherapy (KAP)?

Yes — Klarisana offers KAP, which combines ketamine dosing with structured psychotherapy during the dissociative window. KAP sessions are longer than standalone ketamine sessions and priced accordingly. A reasonable consult question: whether KAP is delivered by a single integrated provider, or by a separate therapist working with the prescribing clinician.

Is Klarisana suited for treatment-resistant depression?

Klarisana treats depression with IM ketamine (off-label, evidence-based), KAP for trauma-anchored depression, and Spravato, the FDA-approved esketamine nasal spray that insurance may cover for treatment-resistant depression. IM ketamine and KAP are usually self-pay. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.

Does Klarisana treat chronic pain conditions?

Yes — Klarisana treats chronic pain. They treat pain with IM ketamine; pain protocols typically use higher cumulative doses than mental-health protocols. Common indications include complex regional pain syndrome (CRPS), fibromyalgia, and certain neuropathic pain syndromes. Pain pricing varies by protocol, so verify how this clinic structures its billing.

Can Klarisana help with anxiety disorders?

Yes — Klarisana treats anxiety, including generalized anxiety, social anxiety, and panic disorder. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines. Worth asking which of their protocols they typically recommend for anxiety-primary patients.

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