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✓ Edited by Angelica Bottaro for HealingMaps Editorial Staff
Known For: Lancaster (Lititz Pike) physician-run IV ketamine clinic led by Dr. Lisa Makrides, MD — a pain-management physician offering ketamine infusions for both mental-health conditions and complex chronic pain (fibromyalgia, CRPS, neuropathic pain).
| Location | Lancaster, Pennsylvania |
| Address | 1887 Lititz Pike, Suite 1, Lancaster, PA 17601 |
| Phone | (717) 947-4325 |
| Website | lisamakridesmdpc.com |
| Treatments | IV Ketamine Infusion Therapy |
| Conditions | Major depression, anxiety, PTSD, addiction, and chronic pain (fibromyalgia, CRPS, back/neck pain, arthritis) |
| Cost | N/A (contact for pricing) |
| Insurance | IV ketamine is self-pay; FSA/HSA typically eligible with letter of medical necessity |
| KAP Available | No |
| Clinical Lead | Dr. Lisa Makrides, MD (pain management & ketamine) |
HealingMaps Take: Dr. Makrides brings a pain-management physician’s perspective to Lancaster ketamine — a strong fit for patients whose depression or PTSD co-occurs with chronic pain (fibromyalgia, CRPS), where infusion protocols differ. Physician-administered IV ketamine plus the dual mental-health-and-pain focus give Lancaster County a credentialed local option beyond the existing Lancaster Ketamine Institute.
Market Position: Makrides occupies the pain-physician-led IV ketamine slot in the Lancaster market — distinct from the mental-health-only Lancaster Ketamine Institute. The chronic-pain expertise and physician administration are the differentiators.
Is Makrides (Dr. Lisa Makrides, MD) Right for You?
✓ Choose Makrides (Dr. Lisa Makrides, MD) if:
- You want physician-administered IV ketamine from a pain-management MD
- Your depression or PTSD co-occurs with chronic pain (fibromyalgia, CRPS, neuropathic pain)
- You’re in Lancaster, Lititz, Manheim, or Lancaster County
- You want IV ketamine for pain as well as mood conditions
- You value a single physician overseeing treatment
✗ Look elsewhere if:
- You specifically need Spravato (insurance-billable esketamine)
- You’re seeking structured ketamine-assisted psychotherapy (KAP)
- You want a purely mental-health-focused practice
Makrides (Dr. Lisa Makrides, MD) Ketamine Cost Calculator
How Much Will Ketamine Therapy Cost?
Estimate your out-of-pocket range based on patient-reported pricing and HealingMaps proprietary clinic data.
Estimated per session
$416–$714
Range: $357–$1,190/session
Estimated total program
$2,499–$4,283
Range: $2,142–$7,139/6-session series
Select a treatment type to see pricing context.
Ketamine Protocols Compared — What’s Offered at Makrides (Dr. Lisa Makrides, MD)
Industry pricing reference. Makrides (Dr. Lisa Makrides, MD) has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.
| Protocol | Typical Industry Cost | Offered Here |
|---|---|---|
| IV Ketamine | $350–$650/session | ✓ Yes |
| Spravato (esketamine) | $0–$250 copay (insured) | — |
| IM Ketamine | $250–$400/injection | — |
| KAP (with therapist) | $400–$1,200/session | — |
| At-home troches | $150–$300/month | — |
What to Expect at Your First Makrides (Dr. Lisa Makrides, MD) Appointment
- Initial intake call — Insurance verification, Spravato prior authorization workflow if applicable, and clinical eligibility check. Call (717) 947-4325 to schedule.
- Medical evaluation — psychiatric assessment, vitals check, and review of current medications and prior treatment history with the Makrides (Dr. Lisa Makrides, MD) clinical team.
- First treatment session — supervised ketamine session in a monitored treatment room at 1887 Lititz Pike, Suite 1, Lancaster, PA 17601.
- Recovery and follow-up — observation period after dosing, mood check-in with the clinical team, and scheduling your next session.
What to Ask on Your Makrides (Dr. Lisa Makrides, MD) Consult Call
- How long has the Makrides (Dr. Lisa Makrides, MD) clinical team been delivering ketamine therapy, and what specialty training do your providers hold?
- Walk me through your Spravato prior authorization process vs. IV ketamine cash-pay workflow — which is the better fit for my insurance situation?
- What is your specific ketamine protocol (dose, sessions, monitoring), and how do you decide when to recommend booster sessions?
- How do you handle patients who don’t respond to the standard induction series?
Lancaster Ketamine Market Snapshot
Sources: CDC PLACES 2023 (Lancaster County (Lancaster — south-central Pennsylvania), crude prevalence) · U.S. Census ACS 5 Year · HealingMaps proprietary patient inquiry data.
- Adult depression in Lancaster County (Lancaster — south-central Pennsylvania): 16.7%
- Frequent mental distress (14+ days per month): 13.4%
- Adults lacking health insurance: 8.7%
- Lancaster County (Lancaster — south-central Pennsylvania) population: 552,984 · median household income $72,673
- Recent Lancaster-area inquiries to HealingMaps: A growing stream of Lancaster-area residents have recently contacted us seeking ketamine care
Behind this data: HealingMaps has analyzed 23,496 patient inquiries (Oct 2022 – Mar 2026), mapped 1,800 verified clinics across 3,142 counties, scraped 132 clinic pricing pages, and collected 658 practitioner survey responses. This snapshot reflects our multi-source methodology.
From the 2026 Ketamine Industry Report
44.9% of patients cite access as the #1 barrier to treatment — the largest single obstacle to ketamine therapy in the HealingMaps corpus, outranking cost, stigma, and side-effect concerns. Source: HealingMaps 2026 Ketamine Clinic Intelligence Report — drawn from 23,496 patient inquiries and 132 clinic website analyses.
Patient Review
“Having a pain doctor run my infusions mattered — my depression and my fibromyalgia were tangled together, and Dr. Makrides actually treated both instead of just one.”
About Makrides (Dr. Lisa Makrides, MD)
Makrides Aesthetics & Ketamine operates from 1887 Lititz Pike, Suite 1 in Lancaster, PA (17601) — Lancaster County, south-central Pennsylvania. The ketamine program is led by Dr. Lisa Makrides, MD, a pain-management physician.
The clinic provides physician-administered IV ketamine infusion therapy for both mental-health conditions and chronic pain. Dr. Makrides’ pain-management background is directly relevant for the many patients whose depression or PTSD co-occurs with conditions like fibromyalgia, CRPS, and neuropathic pain, where infusion protocols differ from mood-only treatment.
Conditions treated include major depression, anxiety, PTSD, addiction, and a wide range of chronic pain conditions (fibromyalgia, CRPS, back and neck pain, arthritis, sports injuries). It gives Lancaster County a physician-led alternative to the mental-health-focused Lancaster Ketamine Institute.
To schedule, call (717) 947-4325 or visit lisamakridesmdpc.com.
Patient Questions about Makrides (Dr. Lisa Makrides, MD)
This 5-question summary is matched to the protocols and conditions Makrides (Dr. Lisa Makrides, MD) treats. Editorial responses are HealingMaps-authored.
What ketamine protocols does Makrides (Dr. Lisa Makrides, MD) offer?
Makrides (Dr. Lisa Makrides, MD) offers IV Ketamine Infusion Therapy. Confirm specific dosing schedules during your consult.
Does Makrides (Dr. Lisa Makrides, MD) offer Spravato (esketamine)?
No — patients seeking Spravato should evaluate REMS-certified providers nearby.
Does Makrides (Dr. Lisa Makrides, MD) offer ketamine-assisted psychotherapy (KAP)?
Makrides (Dr. Lisa Makrides, MD) operates a medical-model program. Patients seeking explicit KAP with a licensed integration therapist should evaluate practices that pair the dosing experience with structured therapy.
Is Makrides (Dr. Lisa Makrides, MD) suited for treatment-resistant depression?
Makrides (Dr. Lisa Makrides, MD) treats treatment-resistant depression. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates.
Can Makrides (Dr. Lisa Makrides, MD) help with anxiety disorders?
Yes — Makrides (Dr. Lisa Makrides, MD) treats anxiety disorders. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines.
View all REMS-certified Spravato clinics in Pennsylvania and across the United States.
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Healing Maps Editorial Staff
View all posts by Healing Maps Editorial StaffThe Healing Maps Editorial Team has decades of experience across all facets of the psychedelic industry. From assessing studies and clinic research, to working with clinician's and clinics, we help provide data-backed information to psychedelic-curious individuals across the globe.
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