5 Best Ketamine Clinics in Chicago (2026) — Verified & Reviewed
Chicago is one of the most active ketamine demand markets in the Midwest. Cook County — home to 5.22 million residents with a 18.7% adult depression prevalence — anchors a mature clinical market with growing Spravato access. More than 50 Illinois residents have recently contacted HealingMaps seeking a ketamine clinic. This guide is the shortlist we send them.
Chicago Ketamine Market Snapshot
Sources: CDC PLACES 2023 (Cook County, IL, crude prevalence) · U.S. Census ACS 5 Year · HealingMaps proprietary patient inquiry data.
- Adult depression in Cook County, IL: 18.7%
- Frequent mental distress (14+ days per month): 16.2%
- Adults lacking health insurance: 11.8%
- Short sleep duration (under 7 hours): 38.7%
- Chicago-area population: 5,225,367 · median household income $78,304
- Recent Chicago-area inquiries to HealingMaps: More than 50 Illinois residents have recently contacted us seeking ketamine care
Behind this data: HealingMaps has analyzed 23,496 patient inquiries (Oct 2022 – Mar 2026), mapped 1,473 verified clinics across 3,142 counties, scraped 132 clinic pricing pages, and collected 658 practitioner survey responses. This snapshot reflects our multi-source methodology.
What this means for you: Chicago operates as a mature ketamine market with both cash-pay and Spravato-insured pathways. Ask every clinic about Spravato REMS certification, FSA/HSA eligibility, and therapy integration support before booking.
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5 Best Ketamine Clinics in Chicago: How We Chose Which Clinics Make the List
Our editorial team evaluated each clinic based on provider credentials, Google and Yelp reviews, treatment options, pricing transparency, and patient experience. We verify that every clinic listed is currently operating and accepting new patients. Clinics that have closed — including Field Trip Health Chicago — have been removed.
The Best Ketamine Clinics in Chicago
1. Hopemark Health Oak Brook (Formerly Wesana Clinics)
| Review Scores | Google: 4.5 (180+ reviews) · Yelp: 3.0 (15 reviews) · Healthgrades: Listed |
| Location | Oak Brook, Illinois |
| Address | 1200 Harger Rd, Suite 830, Oak Brook, IL 60523 |
| Phone | (630) 296-3120 |
| Website | advancedpsychsolutions.com |
| Treatments | IV Ketamine, Spravato (Esketamine), Ketamine-Assisted Therapy, dTMS, EMDR |
| Conditions Treated | Depression, Anxiety, PTSD, OCD, Chronic Pain, Addiction |
| Cost | N/A — contact for pricing |
| Insurance | Spravato covered by insurance; IV ketamine is cash-pay |
| KAP Available? | Yes — integrated ketamine-assisted psychotherapy |
| Clinical Lead | Dr. Abid Nazeer — Board-certified psychiatrist, 4,000+ ketamine treatments administered |
Known For: Chicagoland’s largest ketamine program with 4,000+ treatments and two locations (Oak Brook + downtown Chicago)
Why We Picked Them: Hopemark Health — formerly Wesana Clinics and Advanced Psychiatric Solutions — has the deepest ketamine experience in the Chicago metro. Their psychiatrist-led model combines IV infusions with therapy integration, dTMS, and EMDR under one roof.
The Oak Brook flagship has been a pioneer in the region since its early days as one of the first dedicated ketamine clinics in the western suburbs. Dr. Nazeer’s team offers a comprehensive psychiatric approach rather than standalone infusions, making it a strong fit for patients who want multi-modal treatment.
“Dr. Nazeer and his team truly saved my life. After years of treatment-resistant depression, the ketamine program here gave me hope again. The staff is compassionate and professional.” — Google Review
2. MD Infusions
| Review Scores | Google: 4.9 (60+ reviews) · Yelp: 5.0 (8 reviews) |
| Location | Northbrook, Illinois |
| Address | 1535 Lake Cook Rd, Suite 602, Northbrook, IL 60062 |
| Phone | (844) 463-8734 |
| Website | mdinfusions.com |
| Treatments | IV Ketamine, IM Ketamine |
| Conditions Treated | Depression, Anxiety, PTSD, Chronic Pain, Fibromyalgia, CRPS, Migraines |
| Cost | $495 per infusion |
| Insurance | Cash-pay; superbill provided for out-of-network reimbursement |
| KAP Available? | No |
| Clinical Lead | Physician-led team with 15+ years of experience in anesthesiology and pain management |
Known For: Near-perfect Google reviews (4.9 stars) and specialized chronic pain protocols on Chicago’s North Shore
Why We Picked Them: MD Infusions stands out for its physician-led approach rooted in anesthesiology — giving them particular expertise in pain-related ketamine protocols. Their 4.9-star Google rating reflects consistently positive patient experiences.
Located in Northbrook on Chicago’s North Shore, MD Infusions serves patients across the northern suburbs. Their anesthesiology background makes them especially skilled at dosing and monitoring, and they treat both mood disorders and chronic pain conditions including CRPS and fibromyalgia.
“The entire experience was professional and caring. I’ve seen significant improvement in my depression after just three sessions. The medical staff made me feel safe the entire time.” — Google Review
3. Renew Ketamine & Wellness Center
| Review Scores | Google: 4.8 (50+ reviews) · Yelp: 4.0 (12 reviews) |
| Location | Naperville, Illinois |
| Address | 55 S Main St, Suite 240, Naperville, IL 60540 |
| Phone | (630) 475-1855 |
| Website | chicagolandketamine.com |
| Treatments | IV Ketamine, NAD+ Infusions, IV Hydration Therapy |
| Conditions Treated | Depression, Anxiety, PTSD, OCD, Chronic Pain |
| Cost | N/A — contact for pricing |
| Insurance | Cash-pay; contact clinic for details |
| KAP Available? | No |
| Clinical Lead | Dr. Mansour — Board-certified emergency medicine physician |
Known For: ER physician-led infusion center in downtown Naperville with strong patient satisfaction scores
Why We Picked Them: Renew Ketamine brings emergency medicine expertise to ketamine therapy — Dr. Mansour’s ER background means advanced monitoring and dosing precision. Their downtown Naperville location fills a gap in the western suburbs.
Located above Hugo’s Frog Bar in the heart of downtown Naperville, Renew Ketamine offers a comfortable setting with ample parking. Beyond ketamine, they provide NAD+ and wellness IV infusions. Their ER physician-led model prioritizes safety and clinical rigor during every session.
“Five stars all around. The team is compassionate, empathetic, and really makes you feel seen and valued. The treatment created a shift within me that I honestly did not expect.” — Google Review
4. Imagine Healthcare
| Review Scores | Google: 5.0 (30+ reviews) · Yelp: 5.0 (5 reviews) |
| Location | Chicago, Illinois |
| Address | 680 N Lake Shore Dr, Suite 1260, Chicago, IL 60611 |
| Phone | (773) 484-4744 |
| Website | getimagine.com |
| Treatments | IV Ketamine, IM Ketamine, Ketamine-Assisted Psychotherapy |
| Conditions Treated | Depression, Anxiety, PTSD, Chronic Pain, End-of-Life Distress |
| Cost | N/A — contact for pricing |
| Insurance | Cash-pay; superbill provided |
| KAP Available? | Yes — integrated psychotherapy with ketamine sessions |
| Clinical Lead | Dr. Norris — Board-certified palliative medicine physician |
Known For: Chicago’s first woman-owned ketamine clinic, led by a palliative care physician with deep expertise in end-of-life and existential distress
Why We Picked Them: Imagine Healthcare brings a unique palliative care perspective to ketamine therapy. Dr. Norris’s background in end-of-life medicine adds a layer of compassion and expertise that few ketamine clinics can match, and their KAP integration sets them apart.
Situated in the Streeterville neighborhood on Lake Shore Drive, Imagine Healthcare offers a boutique experience in a premium location. Their focus on ketamine-assisted psychotherapy — not just standalone infusions — makes them ideal for patients seeking deeper therapeutic integration alongside their ketamine treatment.
“Imagine Healthcare is the real deal. Dr. Norris and her team create a warm, safe space. The combination of therapy and ketamine was transformative for my anxiety and depression.” — Google Review
5. Lott Behavioral Health
| Review Scores | Google: 4.9 (40+ reviews) |
| Location | Lisle, Illinois |
| Address | 4320 Winfield Rd, Suite 200, Warrenville, IL 60555 |
| Phone | (630) 730-5506 |
| Website | lottbehavioralhealth.com |
| Treatments | IV Ketamine, IM Ketamine, Spravato (Esketamine) |
| Conditions Treated | Depression, Anxiety, PTSD, Suicidal Ideation, Chronic Pain |
| Cost | $350 per infusion |
| Insurance | Spravato covered by insurance; IV/IM ketamine cash-pay with superbill |
| KAP Available? | No |
| Clinical Lead | Dr. Lott — Board-certified psychiatrist with 6+ years of ketamine experience |
Known For: Most affordable IV ketamine in the Chicago metro at $350/infusion, with transparent pricing and Spravato coverage
Why We Picked Them: Lott Behavioral Health offers the best value in the Chicago area — $350 per infusion is well below the regional average. Their combination of IV ketamine, IM ketamine, and insurance-covered Spravato gives patients multiple treatment pathways.
Located in the western suburbs near Lisle and Warrenville, Lott Behavioral Health has built a loyal patient base over six-plus years. Dr. Lott’s psychiatric training ensures patients receive thorough mental health evaluations before starting ketamine, and the clinic’s smaller size means more personalized attention.
“Dr. Lott is amazing. He takes the time to understand your situation and explains everything clearly. The ketamine treatments have been life-changing for my treatment-resistant depression.” — Google Review
Best Ketamine Clinics in Chicago — In Conclusion
Chicago’s ketamine therapy landscape spans from the Loop to the western suburbs, with options ranging from comprehensive psychiatric programs to focused infusion clinics. Hopemark Health Oak Brook leads with the most experience (4,000+ treatments), while MD Infusions earns the highest patient ratings. Lott Behavioral Health offers the best pricing at $350 per infusion, and Imagine Healthcare provides the deepest therapy integration. We recommend contacting two to three clinics for consultations to find the best fit for your needs.
