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✓ Last verified: March 23, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff
Known For: The NYC area’s largest multi-borough ketamine network — 9 locations across Brooklyn (3), Manhattan, Queens (3), and Bronx (2) — with Medicare/Medicaid in-network status, an access pattern rare among NYC ketamine clinics.
| Location | Brooklyn, New York |
| Address | 2279 Coney Island Ave, Brooklyn, NY 11223 |
| Phone | (718) 998-9890 |
| Website | painfreenyc.com |
| Treatments | IV Ketamine + IM Ketamine + Multiple alternative routes (oral, sublingual, nasal, rectal) |
| Conditions | Depression, treatment-resistant depression, chronic neuropathic pain, fibromyalgia, Complex Regional Pain Syndrome (CRPS), diabetic neuropathy, PTSD, anxiety, oncology pain, prevention of postoperative pain |
| Cost | N/A (contact for pricing) |
| Insurance | IV ketamine is self-pay; FSA/HSA typically eligible with letter of medical necessity |
| KAP Available | No |
| Clinical Lead | Dr. Leon Reyfman, MD |
HealingMaps Take: Pain Physicians NY is the only NYC ketamine practice we’ve verified with 9 locations spanning Brooklyn, Manhattan, Queens, and the Bronx — meaningful geographic coverage for outer-borough patients who can’t easily reach Manhattan. The pain-medicine framing (treats CRPS, neuropathic pain, fibromyalgia, oncology pain alongside depression) means ketamine sits within a broader interventional pain practice. Medicare and Medicaid in-network status is uncommon for ketamine providers.
Market Position: Pain Physicians NY is the only verified multi-borough ketamine network in NYC with explicit Medicare and Medicaid in-network status — patients on government insurance who have hit dead-ends at commercial-only clinics often find this practice works through their plan.
Is Pain Physicians NY Right for You?
✓ Choose Pain Physicians NY if:
- Your ketamine indication is chronic pain (CRPS, neuropathic pain, fibromyalgia, oncology pain) rather than psychiatric only
- You have Medicare or Medicaid and want in-network ketamine coverage (uncommon in NYC ketamine market)
- You’re in Brooklyn, Queens, or the Bronx and want to avoid the trip into Manhattan — 9 locations across all four boroughs
- You want IV ketamine within a broader interventional pain medicine practice including nerve blocks and injections
✗ Look elsewhere if:
- You need Spravato (esketamine) — Pain Physicians NY focuses on IV and IM ketamine, not Spravato
- You’re seeking formal ketamine-assisted psychotherapy (KAP) with structured integration sessions
Pain Physicians NY Ketamine Cost Calculator
How Much Will Ketamine Therapy Cost?
Estimate your out-of-pocket range based on patient-reported pricing and HealingMaps proprietary clinic data.
Estimated per session
$416–$714
Range: $357–$1,190/session
Estimated total program
$2,499–$4,283
Range: $2,142–$7,139/6-session series
Select a treatment type to see pricing context.
Ketamine Protocols Compared — What’s Offered at Pain Physicians NY
Industry pricing reference. Pain Physicians NY has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.
| Protocol | Typical Industry Cost | Offered Here |
|---|---|---|
| IV Ketamine | $350–$650/session | ✓ Yes |
| Spravato (esketamine) | $0–$250 copay (insured) | — |
| IM Ketamine | $250–$400/injection | ✓ Yes |
| KAP (with therapist) | $400–$1,200/session | — |
| At-home troches | $150–$300/month | ✓ Yes |
What to Expect at Your First Pain Physicians NY Appointment
- Initial intake call — Brief medical history review, clinical eligibility check, and intake scheduling. Call (718) 998-9890 to schedule.
- Medical evaluation — in-person or telehealth psychiatric / medical assessment, vitals check, and review of current medications and prior treatment history.
- First treatment session — supervised IV ketamine infusion in a private treatment room, lasting approximately 60–90 minutes. Sessions are held at 2279 Coney Island Ave, Brooklyn, NY 11223.
- Recovery and follow-up — observation period after dosing, mood check-in, and scheduling your next session. Arrange a ride home; do not drive for 24 hours.
What to Ask on Your Pain Physicians NY Consult Call
- How long has the Pain Physicians NY clinical team been delivering ketamine therapy, and what specialty training and board certifications do your providers hold?
- What is your IV ketamine protocol (dose, infusion time, number of sessions), and how do you decide when to recommend booster sessions?
- What is your per-session and full-protocol cash-pay pricing, and do you provide superbills for potential out-of-network insurance reimbursement?
- How do you handle patients who don’t respond to the standard induction series?
Brooklyn Ketamine Market Snapshot
Sources: CDC PLACES 2023 (Kings County (Brooklyn), crude prevalence) · U.S. Census ACS 5 Year · HealingMaps proprietary patient inquiry data.
- Adult depression in Kings County (Brooklyn): 18.4%
- Frequent mental distress (14+ days per month): 13.7%
- Adults lacking health insurance: 8.9%
- Kings County (Brooklyn) population: 2,561,225 · median household income $74,692
- Recent Brooklyn-area inquiries to HealingMaps: A growing stream of Brooklyn-area residents have recently contacted us seeking ketamine care
Behind this data: HealingMaps has analyzed 23,496 patient inquiries (Oct 2022 – Mar 2026), mapped 1,473 verified clinics across 3,142 counties, scraped 132 clinic pricing pages, and collected 658 practitioner survey responses. This snapshot reflects our multi-source methodology.
From the 2026 Ketamine Industry Report
44.9% of patients cite access as the #1 barrier to treatment — the largest single obstacle to ketamine therapy in the HealingMaps corpus, outranking cost, stigma, and side-effect concerns. Source: HealingMaps 2026 Ketamine Clinic Intelligence Report — drawn from 23,496 patient inquiries and 132 clinic website analyses.
Patient Review
“Pain Physicians was the only NYC ketamine clinic that took my Medicare. The Brooklyn location was convenient and they coordinated my ketamine alongside the nerve block plan my pain doctor had already started.” — patient testimonial, paraphrased from public reviews
About Pain Physicians NY
Pain Physicians NY operates 9 ketamine-offering locations across the New York City metro: three in Brooklyn (Coney Island Ave, Downtown Brooklyn, Canarsie), one in Manhattan (240 E 23rd St), three in Queens (Astoria, Rego Park, Jamaica), and two in the Bronx (Crotona Pkwy, Waters Place). The Brooklyn flagship at 2279 Coney Island Avenue serves as the primary intake hub.
Clinical leadership is anchored by Dr. Leon Reyfman, MD, alongside a roster of board-certified pain physicians. The practice operates within a broader interventional pain medicine framework that includes nerve blocks, injections, and other pain interventions — ketamine is one component of a multi-modal pain program.
Conditions treated with ketamine include depression and treatment-resistant depression, chronic neuropathic pain, fibromyalgia, Complex Regional Pain Syndrome (CRPS), diabetic neuropathy, PTSD, anxiety, oncology pain, and prevention of postoperative pain. The clinic emphasizes IV ketamine as the most effective route but also offers IM, oral, sublingual, nasal, and rectal administration based on clinical fit.
Insurance coverage is notably broad: most major plans accepted, with Medicare and Medicaid in-network as Tier 1 provider — uncommon for NYC ketamine clinics. Spravato and formal KAP are not part of the current program. Confirm coverage and intake at (646) 334-4326 (New Patient Coordinator).
Patient Questions about Pain Physicians NY
This 5-question summary is matched to the protocols and conditions Pain Physicians NY treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.
What ketamine protocols does Pain Physicians NY offer?
Pain Physicians NY offers IV ketamine infusion as its primary ketamine protocol.
Does Pain Physicians NY offer Spravato (esketamine)?
No — Pain Physicians NY does not currently offer Spravato (esketamine). Patients seeking insurance-covered Spravato should evaluate clinics with explicit Spravato REMS certification.
Does Pain Physicians NY offer ketamine-assisted psychotherapy (KAP)?
Pain Physicians NY operates a medical-model program rather than a therapy-frame KAP practice. Patients seeking explicit ketamine-assisted psychotherapy with a licensed integration therapist should evaluate clinics that explicitly pair dosing with structured therapy sessions.
Is Pain Physicians NY suited for treatment-resistant depression?
Pain Physicians NY treats depression including treatment-resistant depression. TRD is typically defined as two or more prior antidepressant trials without sufficient response.
Can Pain Physicians NY help with anxiety disorders?
Yes — Pain Physicians NY treats anxiety disorders. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines.
View all REMS-certified Spravato clinics in New York and across the United States.
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Healing Maps Editorial Staff
View all posts by Healing Maps Editorial StaffThe Healing Maps Editorial Team has decades of experience across all facets of the psychedelic industry. From assessing studies and clinic research, to working with clinician's and clinics, we help provide data-backed information to psychedelic-curious individuals across the globe.
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