✓ Last verified: March 27, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff

Known For: Led by Dr. Randall Malchow, a Vanderbilt associate professor and retired Army colonel who was the first Vanderbilt physician to offer intensive ketamine infusion therapy (2014). Over 4,000 infusions completed with physician on-site 100% of the time.
| Review Scores | Google: 5.0 (106 reviews) · 4,000+ infusions completed · Physician present 100% of sessions |
| Location | Franklin, TN (Nashville metro) |
| Address | 1909 Mallory Lane, Suite 300, Franklin, TN 37067 |
| Phone | (615) 813-5006 |
| Website | tnketaminewellness.com |
| Treatments | IV Ketamine Infusions, Intramuscular (IM) Ketamine, Spravato (Esketamine) |
| Conditions Treated | Depression, PTSD, OCD, Anxiety, Alcohol Use Disorder, Chronic Pain |
| Cost | Contact for IV ketamine pricing; Spravato covered by insurance |
| Insurance | Spravato in-network: Aetna, BCBS TN, Medicaid (TN), UHC, Complete Care Support Plan |
| KAP Available? | No (private treatment rooms with continuous monitoring; supplements existing care) |
| Clinical Lead | Dr. Randall Malchow, MD — Board-Certified Anesthesiologist, Vanderbilt Associate Professor, Retired US Army Colonel (25 yrs) |
HealingMaps Take: Dr. Randall Malchow brings credentials that are essentially unmatched in the Nashville ketamine market: Vanderbilt associate professor, retired US Army colonel with 25 years of military medical service, pioneer of ketamine therapy at Vanderbilt (first to offer it there in 2014), and author of 20+ peer-reviewed publications on the topic. With 4,000+ infusions completed and a physician on-site for 100% of sessions, this is the most clinically rigorous ketamine practice in Middle Tennessee. The addition of Spravato with in-network insurance coverage makes treatment accessible for patients with qualifying plans.
Market Position: Tennessee Ketamine Wellness is a Spravato-certified clinic in the Nashville metro. Spravato (esketamine) is the FDA-approved ketamine treatment that most commercial insurance plans cover after prior authorization — unlike cash-pay IV ketamine.
Industry pricing reference. Tennessee Ketamine Wellness has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.
| Protocol | Typical Industry Cost | Offered Here |
|---|---|---|
| IV Ketamine | $350–$650/session | ✓ Yes |
| Spravato (esketamine) | $0–$250 copay (insured) | ✓ Yes |
| IM Ketamine | $250–$400/injection | ✓ Yes |
| KAP (with therapist) | $400–$1,200/session | — |
| At-home troches | $150–$300/month | — |
This 6-question summary is matched to the protocols and conditions Tennessee Ketamine Wellness treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.
Tennessee Ketamine Wellness offers Spravato, IV ketamine and IM ketamine — a 3-protocol practice. Patients can switch between or combine modalities without changing providers. Confirm specific dosing schedules and which protocols are recommended for your condition during your consult.
Yes — Tennessee Ketamine Wellness offers Spravato, which means they’re FDA REMS-certified and maintain the required two-hour in-office monitoring window after each dose. Spravato is the primary insurance-covered ketamine option for treatment-resistant depression. Worth confirming the prior-authorization timeline before booking your first session.
Tennessee Ketamine Wellness treats depression via Spravato (FDA-approved for TRD), and IV ketamine (off-label, evidence-based). The Spravato pathway is the most likely to obtain commercial insurance coverage. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.
Yes — Tennessee Ketamine Wellness treats chronic pain. They use IV ketamine for pain, which typically means longer infusion times and higher cumulative doses than mental-health protocols. Common indications include complex regional pain syndrome (CRPS), fibromyalgia, and certain neuropathic pain syndromes. Pain pricing varies significantly by structure: per-infusion vs. multi-day inpatient packages — verify how this clinic structures their billing.
Yes — Tennessee Ketamine Wellness treats PTSD. Both Spravato and IV ketamine can be used for trauma. Ketamine for trauma differs from depression treatment: dosing is often lower per session, and pairing the protocol with trauma-focused therapy between sessions is common. A reasonable consult question: whether PTSD patients here typically use ketamine alone or alongside an outside therapist.
Yes — Tennessee Ketamine Wellness treats anxiety, including generalized anxiety, social anxiety, and panic disorder. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines. Worth asking which of their protocols they typically recommend for anxiety-primary patients.
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