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✓ Last verified: April 24, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff

Tremayne Medicine in Modesto, California logo

Known For: Tremayne Medicine is a Modesto-based integrative practice led by Dr. Paula Tremayne that combines primary care, chiropractic services, and ketamine infusion therapy. Their ketamine program targets treatment-resistant depression, PTSD, and anxiety, offering Central Valley patients access to this advanced treatment without traveling to the Bay Area or Sacramento.

Review Scores⭐ 4.3 (Based on Google Reviews)
LocationModesto, California
Address817 Coffee Road, Bldg D, Modesto, CA 95355
Phone(209) 549-1600
Websitetremaynemedicine.com
TreatmentsIV Ketamine Infusions, Primary Care, Chiropractic Care
Conditions TreatedDepression, Anxiety, PTSD, Chronic Pain
CostContact clinic for current pricing
InsuranceContact clinic for insurance details
KAP Available?No
Clinical LeadDr. Paula Tremayne

💡 No clinic-specific pricing posted? See our ketamine therapy cost guide for typical pricing ranges by treatment type and insurance pathways.

HealingMaps Take: Tremayne Medicine is one of the few ketamine providers in the Central Valley, filling a significant access gap for patients in Modesto, Turlock, and surrounding communities. The integrative model — combining primary care with ketamine therapy — allows Dr. Tremayne’s team to manage the whole patient, not just the ketamine treatment, which can be beneficial for those with complex health needs.

Market Position: Tremayne Medicine treats both depression and PTSD — the two most common ketamine therapy indications, accounting for 34% of HealingMaps patient inquiries.

Is Tremayne Medicine Right for You?

✓ Choose Tremayne Medicine if:

  • You’re treating co-occurring depression and PTSD

✗ Look elsewhere if:

  • You want ketamine-assisted psychotherapy (KAP) with integrated talk therapy

Tremayne Medicine Ketamine Cost Calculator

How Much Will Ketamine Therapy Cost?

Estimate your out-of-pocket range based on patient-reported pricing and HealingMaps proprietary clinic data.
Estimated per session
$525–$900
Range: $450–$1,500/session
Estimated total program
$3,150–$5,400
Range: $2,700–$9,000/6-session series
Your estimate vs. national patient-reported median Based on national tracking, adjusted for Los Angeles, CA market
Select a treatment type to see pricing context.

Ketamine Protocols Compared — What’s Offered at Tremayne Medicine

Industry pricing reference. Tremayne Medicine has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.

ProtocolTypical Industry CostOffered Here
IV Ketamine Infusion$350–$650/session
Spravato (esketamine)$0–$250 copay (insured)
IM Ketamine$250–$400/injection
KAP (with integrated talk therapy)$400–$1,200/session
At-home oral troches$150–$300/month

What to Expect at Your First Tremayne Medicine Appointment

  1. Initial intake call — Medical history review and clinical eligibility check. Call (209) 549-1600 to schedule.
  2. Medical evaluation — in-person or telehealth psychiatric assessment, vitals check, and review of current medications with the Tremayne Medicine clinical team.
  3. First treatment session — supervised ketamine therapy session in a private treatment room, lasting approximately 60–90 minutes. Sessions are held at 817 Coffee Road, Bldg D, Modesto, CA 95355. You’ll have a comfortable chair or recliner, dim lighting, and direct medical monitoring throughout.
  4. Recovery and follow-up — observation period after dosing, mood check-in with the clinical team, and scheduling your next session. Arrange for a ride home; do not drive for 24 hours after your ketamine session.

What to Ask on Your Tremayne Medicine Consult Call

  • How long has the Tremayne Medicine clinical team been delivering ketamine therapy, and what specialty training do your providers hold?
  • What’s a typical 6-session total cost at Tremayne Medicine, and do you offer payment plans, HSA/FSA-eligible billing, or sliding-scale pricing?
  • California’s psychedelic-therapy regulatory landscape is evolving — do you stay current with state Department of Public Health and Medical Board guidance on ketamine prescribing?
  • What does Tremayne Medicine recommend for patients who don’t respond to the standard 6-session acute series?

Patient Questions about Tremayne Medicine

This 4-question summary is matched to the protocols and conditions Tremayne Medicine treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.

Is Tremayne Medicine suited for treatment-resistant depression?

Tremayne Medicine treats depression via IV ketamine (off-label, evidence-based). Insurance coverage is rare for IV/KAP — most patients pay out of pocket. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.

Does Tremayne Medicine treat chronic pain conditions?

Yes — Tremayne Medicine treats chronic pain. They use IV ketamine for pain, which typically means longer infusion times and higher cumulative doses than mental-health protocols. Common indications include complex regional pain syndrome (CRPS), fibromyalgia, and certain neuropathic pain syndromes. Pain pricing varies significantly by structure: per-infusion vs. multi-day inpatient packages — verify how this clinic structures their billing.

Does Tremayne Medicine treat PTSD?

Yes — Tremayne Medicine treats PTSD. Ketamine for trauma differs from depression treatment: dosing is often lower per session, and pairing the protocol with trauma-focused therapy between sessions is common. A reasonable consult question: whether PTSD patients here typically use ketamine alone or alongside an outside therapist.

Can Tremayne Medicine help with anxiety disorders?

Yes — Tremayne Medicine treats anxiety, including generalized anxiety, social anxiety, and panic disorder. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines. Worth asking which of their protocols they typically recommend for anxiety-primary patients.

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Healing Maps Editorial Staff

Healing Maps Editorial Staff

View all posts by Healing Maps Editorial Staff

The Healing Maps Editorial Team has decades of experience across all facets of the psychedelic industry. From assessing studies and clinic research, to working with clinician's and clinics, we help provide data-backed information to psychedelic-curious individuals across the globe.

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