✓ Last verified: April 24, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff

Known For: Tremayne Medicine is a Modesto-based integrative practice led by Dr. Paula Tremayne that combines primary care, chiropractic services, and ketamine infusion therapy. Their ketamine program targets treatment-resistant depression, PTSD, and anxiety, offering Central Valley patients access to this advanced treatment without traveling to the Bay Area or Sacramento.
| Review Scores | ⭐ 4.3 (Based on Google Reviews) |
| Location | Modesto, California |
| Address | 817 Coffee Road, Bldg D, Modesto, CA 95355 |
| Phone | (209) 549-1600 |
| Website | tremaynemedicine.com |
| Treatments | IV Ketamine Infusions, Primary Care, Chiropractic Care |
| Conditions Treated | Depression, Anxiety, PTSD, Chronic Pain |
| Cost | Contact clinic for current pricing |
| Insurance | Contact clinic for insurance details |
| KAP Available? | No |
| Clinical Lead | Dr. Paula Tremayne |
💡 No clinic-specific pricing posted? See our ketamine therapy cost guide for typical pricing ranges by treatment type and insurance pathways.
HealingMaps Take: Tremayne Medicine is one of the few ketamine providers in the Central Valley, filling a significant access gap for patients in Modesto, Turlock, and surrounding communities. The integrative model — combining primary care with ketamine therapy — allows Dr. Tremayne’s team to manage the whole patient, not just the ketamine treatment, which can be beneficial for those with complex health needs.
Market Position: Tremayne Medicine treats both depression and PTSD — the two most common ketamine therapy indications, accounting for 34% of HealingMaps patient inquiries.
Industry pricing reference. Tremayne Medicine has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.
| Protocol | Typical Industry Cost | Offered Here |
|---|---|---|
| IV Ketamine Infusion | $350–$650/session | ✓ |
| Spravato (esketamine) | $0–$250 copay (insured) | — |
| IM Ketamine | $250–$400/injection | — |
| KAP (with integrated talk therapy) | $400–$1,200/session | — |
| At-home oral troches | $150–$300/month | — |
This 4-question summary is matched to the protocols and conditions Tremayne Medicine treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.
Tremayne Medicine treats depression via IV ketamine (off-label, evidence-based). Insurance coverage is rare for IV/KAP — most patients pay out of pocket. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.
Yes — Tremayne Medicine treats chronic pain. They use IV ketamine for pain, which typically means longer infusion times and higher cumulative doses than mental-health protocols. Common indications include complex regional pain syndrome (CRPS), fibromyalgia, and certain neuropathic pain syndromes. Pain pricing varies significantly by structure: per-infusion vs. multi-day inpatient packages — verify how this clinic structures their billing.
Yes — Tremayne Medicine treats PTSD. Ketamine for trauma differs from depression treatment: dosing is often lower per session, and pairing the protocol with trauma-focused therapy between sessions is common. A reasonable consult question: whether PTSD patients here typically use ketamine alone or alongside an outside therapist.
Yes — Tremayne Medicine treats anxiety, including generalized anxiety, social anxiety, and panic disorder. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines. Worth asking which of their protocols they typically recommend for anxiety-primary patients.
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