✓ Last verified: January 30, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff
Known For: Tucson’s premier ketamine-assisted psychotherapy (KAP) practice, led by a dual board-certified PMHNP who combines oral ketamine with intensive preparation and integration therapy for lasting mental health transformation.
| Review Scores | Positive patient feedback; patients highlight trauma-informed care and clinical depth |
| Location | Tucson, AZ |
| Address | 3210 E Fort Lowell Rd, Suite 103, Tucson, AZ 85716 |
| Phone | (520) 505-0290 |
| Website | wilywellness.com |
| Treatments | Ketamine-Assisted Psychotherapy (KAP), Oral Ketamine, Preparation & Integration Sessions |
| Conditions Treated | Treatment-Resistant Depression, PTSD, Anxiety, OCD, Chronic Pain, End-of-Life Distress |
| Cost | $595 per KAP session; packages available |
| Insurance | Not accepted for ketamine services; superbill may be provided |
| KAP Available? | Yes — core offering with deep preparation and integration |
| Clinical Lead | Dr. Heather Carlisle, PMHNP-BC — Dual Board-Certified Psychiatric Mental Health Nurse Practitioner |
HealingMaps Take: Wily Wellness stands out in the Tucson market because it is a genuine ketamine-assisted psychotherapy practice — not just an infusion clinic that bolts on a therapy referral. Dr. Heather Carlisle is a dual board-certified Psychiatric Mental Health Nurse Practitioner who built this practice around the principle that ketamine works best when embedded in a therapeutic relationship. Each $595 KAP session includes preparation, a guided oral ketamine experience, and integration work — the three-legged stool that research consistently shows produces the most durable outcomes. The oral route (sublingual lozenges) is intentional: it produces a gentler, longer experience that is more conducive to psychotherapeutic work than the dissociative peak of IV infusion. For Tucson patients who have tried antidepressants, talk therapy, or even IV ketamine without lasting results, Wily Wellness offers something fundamentally different — a model where the medicine and the therapy are not separate services but a single integrated experience. The practice also treats chronic pain and end-of-life distress, reflecting Dr. Carlisle’s understanding that ketamine’s applications extend well beyond depression.
Market Position: Wily Wellness treats both depression and PTSD — the two most common ketamine therapy indications, accounting for 34% of HealingMaps patient inquiries.
Industry pricing reference. Wily Wellness’s posted price: $595 per KAP session; packages available. Contact the clinic for any package or sliding-scale options. The calculator above shows metro-level cost estimates across protocols.
| Protocol | Typical Industry Cost | Offered Here |
|---|---|---|
| IV Ketamine | $350–$650/session | — |
| Spravato (esketamine) | $0–$250 copay (insured) | — |
| IM Ketamine | $250–$400/injection | — |
| KAP (with therapist) | $400–$1,200/session | ✓ Yes |
| At-home troches | $150–$300/month | ✓ Yes |
Sources: CDC PLACES 2023 (Pima County, AZ, crude prevalence) · U.S. Census ACS 5 Year · HealingMaps proprietary patient inquiry data.
Behind this data: HealingMaps has analyzed 23,496 patient inquiries (Oct 2022 – Mar 2026), mapped 1,473 verified clinics across 3,142 counties, scraped 132 clinic pricing pages, and collected 658 practitioner survey responses. This snapshot reflects our multi-source methodology.
13.5% of ketamine inquiries specifically cite PTSD — second only to depression as a driver of patient demand in the HealingMaps corpus. Source: HealingMaps 2026 Ketamine Clinic Intelligence Report — drawn from 23,496 patient inquiries and 132 clinic website analyses.
This 4-question summary is matched to the protocols and conditions Wily Wellness treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.
Yes — Wily Wellness offers KAP, which combines ketamine dosing with structured psychotherapy during the dissociative window. KAP sessions are longer than standalone infusions and priced accordingly. A reasonable consult question: whether KAP is delivered by a single integrated provider, or by a separate therapist working with the prescribing clinician.
Wily Wellness treats depression via KAP for trauma-anchored depression. Insurance coverage is rare for IV/KAP — most patients pay out of pocket. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.
Yes — Wily Wellness treats chronic pain. Common indications include complex regional pain syndrome (CRPS), fibromyalgia, and certain neuropathic pain syndromes. Pain pricing varies significantly by structure: per-infusion vs. multi-day inpatient packages — verify how this clinic structures their billing.
Yes — Wily Wellness treats anxiety, including generalized anxiety, social anxiety, and panic disorder. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines. Worth asking which of their protocols they typically recommend for anxiety-primary patients.
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