7 Best Ketamine Clinics in San Diego (2026) — Verified & Reviewed
San Diego has become one of Southern California’s most active markets for ketamine therapy, with clinics ranging from pioneering research-driven practices to integrative wellness centers. For patients struggling with treatment-resistant depression, anxiety, PTSD, or chronic pain, the options here are strong and varied.
We researched every ketamine clinic in San Diego County, verified credentials, checked patient reviews across Google and Yelp, and confirmed each clinic is currently open and accepting new patients. Below are the seven best options for 2026.
7 Best Ketamine Clinics in San Diego: How Did We Decide Which Clinics Make Our List?
We evaluated clinics based on clinical leadership credentials, patient review scores, treatment modalities offered, pricing transparency, years of operation, and overall patient experience. Clinics with published research, board-certified specialists, and strong review profiles scored highest.
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| Review Scores | Google: 4.9 · Yelp: 4.5 (32 reviews) |
| Location | La Jolla, California |
| Address | 3252 Holiday Ct, Suite 112, La Jolla, CA 92037 |
| Phone | (858) 898-4110 |
| Website | kadimanp.com |
| Treatments | IV Ketamine, Spravato, TMS, Psychedelic-Assisted Therapy |
| Conditions Treated | Depression, Anxiety, PTSD, OCD, Bipolar |
| Cost | Contact for pricing |
| Insurance | Spravato and TMS covered by insurance; IV ketamine cash-pay |
| KAP Available? | Yes — psychedelic-assisted therapy program |
| Clinical Lead | Dr. David Feifel, MD, PhD — Established world’s first ketamine infusion clinic at UCSD in 2008 |
Known For: Founded by the physician who opened the world’s first ketamine infusion clinic at UCSD in 2008 — Scripps-affiliated
Why We Picked Them: Dr. David Feifel literally pioneered clinical ketamine therapy. He established the world’s first ketamine infusion clinic at UC San Diego in 2008, and his private practice at Kadima carries that same research-driven approach. The clinic is Scripps-affiliated, adding another layer of clinical credibility.
Kadima offers the broadest treatment menu in San Diego — IV ketamine, Spravato, TMS, and psychedelic-assisted therapy — allowing the team to match the right modality to each patient. Patients consistently describe feeling that the entire staff is genuinely invested in their recovery, with multiple reviews noting they were able to taper off SSRIs after starting ketamine treatment.
“Ketamine was very effective right away. I was able to get off SSRIs that had been nearly impossible to taper off before I went to Kadima.” — Google Review
2. Resilience Integrative Wellness
| Review Scores | Google: 4.9 · Yelp: 5.0 (24 reviews) |
| Location | San Diego, California |
| Address | 6719 Alvarado Rd, Suite 201, San Diego, CA 92120 |
| Phone | (619) 535-5528 |
| Website | resilienceintegrative.com |
| Treatments | IV Ketamine, Spravato, TMS |
| Conditions Treated | Depression, Anxiety, PTSD, Chronic Pain |
| Cost | Most affordable ketamine clinic in San Diego (per patient reviews) |
| Insurance | Spravato and TMS covered by insurance; IV ketamine cash-pay |
| KAP Available? | No |
| Clinical Lead | Clinical team with 30+ years combined ketamine experience |
Known For: Most affordable ketamine clinic in San Diego with six private treatment rooms, SoundSelf technology, and a spa-like experience
Why We Picked Them: Resilience Integrative Wellness earns consistently top marks from patients for combining clinical quality with the best pricing in San Diego. Multiple reviewers specifically note they shopped around and found Resilience to be the most affordable option without sacrificing care quality.
The clinic features six treatment rooms equipped with Bose noise-canceling headphones, reclining chairs, warm blankets, and complimentary refreshments. They also offer SoundSelf technology — a therapeutic VR experience — before or after sessions. With over 30 years of experience safely administering ketamine, the team brings deep clinical expertise to an accessible, welcoming environment.
“Resilience is one of the best ketamine centers I’ve visited. The staff is caring, attentive, positive, and genuinely care about your well-being.” — Yelp Review
3. Kai MacDonald Ketamine Clinic
| Review Scores | Google: 5.0 |
| Location | San Diego, California (Bankers Hill) |
| Address | 3368 2nd Ave, Suite B, San Diego, CA 92103 |
| Phone | Contact via website |
| Website | kaimacdonald.com |
| Treatments | IV Ketamine, Ketamine-Assisted Psychotherapy |
| Conditions Treated | Depression, Anxiety, PTSD, OCD, Addiction, ADHD |
| Cost | $300–$500 per treatment |
| Insurance | Concierge model — outside insurance system |
| KAP Available? | Yes — integrated psychotherapy with ketamine |
| Clinical Lead | Dr. Kai MacDonald, MD — Concierge psychiatrist |
Known For: Concierge psychiatry model — no insurance middlemen, extended appointments, and whole-person treatment including lifestyle and diet
Why We Picked Them: Dr. Kai MacDonald runs a boutique concierge practice where patients get something rare in modern psychiatry: time. Separated from the insurance-based model, appointments are longer, treatment plans are deeply individualized, and the doctor-patient relationship is the foundation of care.
The holistic approach extends beyond ketamine to lifestyle factors including diet, exercise, and stress management. At $300-$500 per treatment, pricing is competitive for a concierge practice, and the Bankers Hill location in central San Diego is convenient. For patients who want a psychiatrist who treats the whole person rather than just prescribing medication, this clinic is a standout.
“Dr. MacDonald truly cares about his patients. The personalized approach and extended appointment times made all the difference in my treatment.” — Google Review
4. Point Loma Clinic
| Review Scores | Google: 4.8 |
| Location | San Diego, California (Point Loma) |
| Address | 2918 Emerson St, San Diego, CA 92106 |
| Phone | (858) 429-5841 |
| Website | pointlomaclinic.com |
| Treatments | IV Ketamine, Ketamine-Assisted Psychotherapy |
| Conditions Treated | Depression, Anxiety, PTSD, OCD, Bipolar |
| Cost | Contact for pricing |
| Insurance | Contact for details |
| KAP Available? | Yes — ketamine combined with psychotherapy |
| Clinical Lead | Dr. Alexander Papp, MD — Board-certified psychiatrist (25+ years) |
Known For: One-on-one ketamine sessions with the psychiatrist — no other patients treated simultaneously, in a warm home-like setting
Why We Picked Them: Point Loma Clinic offers something truly rare: during your 2-hour ketamine session, Dr. Papp is with you and only you. No other patients are receiving treatment at the same time, ensuring undivided attention from a psychiatrist with over 25 years of clinical experience.
The clinic’s warm, homey environment is a deliberate departure from sterile medical offices — patients describe feeling relaxed and comfortable from the moment they walk in. Each treatment visit is scheduled for two hours, with the ketamine effect lasting 40-70 minutes and the rest dedicated to preparation and integration. For patients who value privacy and personal attention above all else, Point Loma Clinic delivers.
“The warm and homey environment immediately put me at ease. Dr. Papp is genuinely caring and knowledgeable — I felt completely safe throughout my treatment.” — Google Review
5. Luma Health & Wellness
| Review Scores | Google: 4.9 |
| Location | Solana Beach, California (North County San Diego) |
| Address | 462 Stevens Ave, Suite 310, Solana Beach, CA 92075 |
| Phone | (858) 617-0004 |
| Website | lumawellnesscenter.com |
| Treatments | IV Ketamine, Intranasal Esketamine, KAP, Integrative Psychiatry |
| Conditions Treated | Depression, Anxiety, PTSD, Chronic Pain |
| Cost | Contact for pricing; financing available |
| Insurance | Esketamine may be covered; IV ketamine cash-pay |
| KAP Available? | Yes — ketamine-assisted psychotherapy with licensed therapists |
| Clinical Lead | Dr. Troy Kurz — Integrative psychiatrist |
Known For: Integrative psychiatry approach combining ketamine with naturopathic care, therapy, and medication management
Why We Picked Them: Luma Health & Wellness takes an integrative approach that sets it apart from single-modality clinics. Under Dr. Troy Kurz’s leadership, the clinic combines ketamine therapy with naturopathic care, psychotherapy, and psychiatric medication management — treating the whole patient rather than just the symptoms.
Located in Solana Beach, Luma serves North County San Diego communities including Carlsbad, Encinitas, Del Mar, La Jolla, and Rancho Santa Fe. Established in 2023, the clinic is newer but has quickly built a strong reputation, earning a 4.9 Google rating. Their personalized approach and Dr. Kurz’s deep expertise in both conventional and integrative psychiatry make this a standout option for patients seeking comprehensive care.
“Dr. Kurz is incredibly knowledgeable and compassionate. The personalized treatment plan they created for me has made a world of difference.” — Google Review
6. Medical Man Cave
| Review Scores | Google: 4.8 |
| Location | San Diego, California (Pacific Beach) |
| Address | 3023 Bunker Hill St, Suite 203, San Diego, CA 92109 |
| Phone | (619) 492-5926 |
| Website | medmancave.com |
| Treatments | IV Ketamine |
| Conditions Treated | Treatment-Resistant Depression, Mood Disorders |
| Cost | Contact for pricing |
| Insurance | Cash-pay |
| KAP Available? | No |
| Clinical Lead | Multidisciplinary team from various health backgrounds |
Known For: Men’s health-focused clinic in Pacific Beach offering ketamine alongside a full suite of wellness services
Why We Picked Them: Medical Man Cave is a men’s health clinic that has added ketamine therapy to its menu of services, bringing a unique perspective to mental health treatment. The diverse medical team creates individualized treatment plans in a collaborative, non-judgmental environment that resonates particularly well with male patients who may be hesitant about traditional psychiatric settings.
Located in Pacific Beach, the clinic’s relaxed coastal vibe is a welcome departure from sterile clinical environments. While the ketamine offering is part of a broader wellness practice rather than a dedicated ketamine clinic, the medical oversight and individualized approach ensure patients receive safe, professionally administered treatment.
“Great experience overall. The staff made me feel comfortable from the start and the treatment has made a real difference in my daily life.” — Google Review
7. Achieve Medical
| Review Scores | Google: 4.7 |
| Location | San Diego, California (University City) |
| Address | 5060 Shoreham Pl, Suite 330, San Diego, CA 92122 |
| Phone | Contact via website |
| Website | achievemedical.com |
| Treatments | IV Ketamine, Nasal Esketamine, Psychotherapy |
| Conditions Treated | Treatment-Resistant Depression, ADHD, Anxiety |
| Cost | Contact for pricing |
| Insurance | Contact for details |
| KAP Available? | Yes — ketamine used to complement psychotherapy |
| Clinical Lead | Psychiatric team specializing in treatment-resistant conditions |
Known For: Dual focus on treatment-resistant depression and ADHD — combining ketamine with ongoing psychotherapy
Why We Picked Them: Achieve Medical takes a comprehensive psychiatric approach, using ketamine and esketamine as tools within a broader treatment framework rather than as standalone interventions. Their dual specialty in both treatment-resistant depression and ADHD means they understand the complex interplay between these conditions that often co-occur.
The clinic prioritizes individualized therapy with warm, welcoming facilities in the University City area near UCSD. Both nasal esketamine and IV ketamine infusions are available, complementing their psychotherapy services. For patients who want ketamine therapy integrated into a full psychiatric care plan rather than visiting a standalone infusion clinic, Achieve Medical offers that continuity.
“The team at Achieve Medical truly listens and creates a treatment plan that works for you as an individual. Highly recommend.” — Google Review
