✓ Last verified: March 19, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff

Known For: Center for Optimal Living is a Midtown Manhattan practice specializing in ketamine-assisted psychotherapy with a unique Integrative Harm Reduction Psychotherapy (IHRP) approach. The clinic is particularly known for serving patients battling addiction, offering personalized care that respects individual choices between moderation and abstinence—a progressive model in the ketamine therapy space.
| Google Reviews | ⭐ NYC psychedelic therapy center |
| Location | New York, New York (Midtown) |
| Address | 370 Lexington Avenue, Suite 500, New York, NY 10017 |
| Phone | (212) 213-8905 |
| Website | centerforoptimalliving.com |
| Treatments | Ketamine-Assisted Psychotherapy, IHRP, Psychedelic Therapy |
| Conditions Treated | Addiction, Depression, Anxiety, Trauma |
| Cost | Contact clinic; limited insurance compatibility |
| Insurance | Limited insurance accepted; contact for details |
| KAP Available | Yes — core service with harm reduction framework |
| Clinical Lead | Highly trained psychedelic therapy team |
HealingMaps Take: Center for Optimal Living occupies a unique niche in NYC’s ketamine landscape with their harm reduction and addiction-focused approach. Their IHRP model is especially valuable for patients whose substance use issues intersect with depression or trauma—a population often underserved by standard ketamine clinics. The Midtown location is convenient but high demand may mean longer wait times for initial consultations. Worth the wait for patients seeking a deeply therapeutic, non-judgmental ketamine experience.
Market Position: Center for Optimal Living is a verified ketamine provider in the York metro on HealingMaps — one of 1,473 clinics we have mapped and tracked across 3,142 U.S. counties.
Industry pricing reference. Center for Optimal Living has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.
| Protocol | Typical Industry Cost | Offered Here |
|---|---|---|
| IV Ketamine | $350–$650/session | — |
| Spravato (esketamine) | $0–$250 copay (insured) | — |
| IM Ketamine | $250–$400/injection | — |
| KAP (with therapist) | $400–$1,200/session | ✓ Yes |
| At-home troches | $150–$300/month | — |
This 3-question summary is matched to the protocols and conditions Center for Optimal Living treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.
Yes — Center for Optimal Living offers KAP, which combines ketamine dosing with structured psychotherapy during the dissociative window. KAP sessions are longer than standalone infusions and priced accordingly. A reasonable consult question: whether KAP is delivered by a single integrated provider, or by a separate therapist working with the prescribing clinician.
Center for Optimal Living treats depression via KAP for trauma-anchored depression. Insurance coverage is rare for IV/KAP — most patients pay out of pocket. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.
Yes — Center for Optimal Living treats anxiety, including generalized anxiety, social anxiety, and panic disorder. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines. Worth asking which of their protocols they typically recommend for anxiety-primary patients.
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