✓ Last verified: April 4, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff
Known For: Clínica Synaptica is a Barcelona-based clinic specializing in ketamine-assisted psychotherapy and psychedelic-informed mental health treatment. Located in the Eixample district near Trafalgar, the clinic offers ketamine therapy for treatment-resistant depression, anxiety, PTSD, and trauma within a European clinical framework that integrates neuroscience with psychotherapeutic support.
HealingMaps Take: Clínica Synaptica is one of the few dedicated ketamine therapy clinics in Spain, making it a notable option for patients in Barcelona and across the Iberian Peninsula. Their neuroscience-informed, psychedelic-assisted approach aligns with the latest research in the field. A perfect 5.0 Google rating and central Barcelona location make them a top choice for European patients seeking KAP.
Market Position: Clínica Synaptica treats both depression and PTSD — the two most common ketamine therapy indications, accounting for 34% of HealingMaps patient inquiries.
Is Clínica Synaptica Right for You?
✓ Choose Clínica Synaptica if:
You’re seeking ketamine-assisted psychotherapy (KAP) with a licensed therapist alongside dosing
You’re treating co-occurring depression and PTSD
✗ Look elsewhere if:
You’re seeking ketamine for chronic pain (this clinic focuses on mental health)
Ketamine Protocols Compared — What’s Offered at Clínica Synaptica
Industry pricing reference. Clínica Synaptica has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.
Protocol
Typical Industry Cost
Offered Here
IV Ketamine
$350–$650/session
—
Spravato (esketamine)
$0–$250 copay (insured)
—
IM Ketamine
$250–$400/injection
—
KAP (with therapist)
$400–$1,200/session
✓ Yes
At-home troches
$150–$300/month
—
What to Expect at Your First Clínica Synaptica Appointment
Initial intake call — Medical history review and clinical eligibility check. Call +34 613 04 72 82 or visit clinicasynaptica.com to schedule.
Medical evaluation — in-person or telehealth psychiatric assessment, vitals check, and review of current medications with the Clínica Synaptica clinical team.
First treatment session — supervised ketamine therapy session in a private treatment room, lasting approximately 60–90 minutes. Sessions are held at Trafalgar, 4, 6-B, 08010 Barcelona. You’ll have a comfortable chair or recliner, dim lighting, and direct medical monitoring throughout.
Recovery and follow-up — observation period after dosing, mood check-in with the clinical team, and scheduling your next session. Arrange for a ride home; do not drive for 24 hours after your ketamine session.
What to Ask on Your Clínica Synaptica Consult Call
How long has the Clínica Synaptica clinical team been delivering ketamine therapy, and what specialty training do your providers hold?
What’s Clínica Synaptica’s typical full-program cost for the integration-therapy bundle, and do you accept HSA/FSA payments?
Is the therapist who guides KAP sessions independently licensed, and how long are integration sessions after the dosing portion?
What does Clínica Synaptica recommend for patients who don’t respond to the standard 6-session acute series?
Ketamine Market Snapshot
Sources: CDC PLACES 2023 (Burlington County, , crude prevalence) · U.S. Census ACS 5 Year · HealingMaps proprietary patient inquiry data.
Adult depression in Burlington County, : 16.3%
Frequent mental distress (14+ days per month): 16.1%
Adults lacking health insurance: 8.3%
Burlington County population: 461,853 · median household income $102,615
Recent -area inquiries to HealingMaps: A growing stream of residents have recently contacted us seeking ketamine care
Behind this data:HealingMaps has analyzed 23,496 patient inquiries (Oct 2022 – Mar 2026), mapped 1,473 verified clinics across 3,142 counties, scraped 132 clinic pricing pages, and collected 658 practitioner survey responses. This snapshot reflects our multi-source methodology.
From the 2026 Ketamine Industry Report
44.9% of patients cite access as the #1 barrier to treatment — the largest single obstacle to ketamine therapy in the HealingMaps corpus, outranking cost, stigma, and side-effect concerns. Source: HealingMaps 2026 Ketamine Clinic Intelligence Report — drawn from 23,496 patient inquiries and 132 clinic website analyses.
Patient Review
“Clínica Synaptica provided an exceptional experience. The team was knowledgeable, compassionate, and the ketamine-assisted therapy sessions were conducted with the highest professionalism.” — Clínica Synaptica Patient
Clínica Synaptica provides patients with hope for healing through the use of ketamine therapy services. Ketamine therapy is a relatively new treatment modality that can be used to effectively treat pain and mood disorders that are resistant to traditional medicine. While ketamine can be used for various conditions, it is most effective for depression and that is the condition focused on at the wellness clinic.
As the first ketamine clinic in Barcelona, the team at Clínica Synaptica hopes to change how people approach depression treatment. The medical professionals that own and operate the clinic are considered pioneers in their fields and share a true passion for medical innovation and healthier patients.
This 3-question summary is matched to the protocols and conditions Clínica Synaptica treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.
Does Clínica Synaptica offer ketamine-assisted psychotherapy (KAP)?
Yes — Clínica Synaptica offers KAP, which combines ketamine dosing with structured psychotherapy during the dissociative window. KAP sessions are longer than standalone infusions and priced accordingly. A reasonable consult question: whether KAP is delivered by a single integrated provider, or by a separate therapist working with the prescribing clinician.
Is Clínica Synaptica suited for treatment-resistant depression?
Clínica Synaptica treats depression via KAP for trauma-anchored depression. Insurance coverage is rare for IV/KAP — most patients pay out of pocket. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.
Can Clínica Synaptica help with anxiety disorders?
Yes — Clínica Synaptica treats anxiety, including generalized anxiety, social anxiety, and panic disorder. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines. Worth asking which of their protocols they typically recommend for anxiety-primary patients.
Angelica Bottaro is a medical writer and researcher with a rich background in psychology and journalism. She holds a bachelor's degree in Psychology from Trent University and an Advanced Diploma in Journalism from Centennial College. Angelica has been a freelance writer since 2014, amassing bylines in various platforms like Very Well Health, The Good Men Project, MakeWell, and LymeTime among others. Although primarily a freelance writer, her educational background and career trajectory have positioned her as a voice in mental health discourse, highlighting systemic issues in mental health care through her writing.
Flora Patricia Sirkia
May 31, 2024 at 4:54 pmGreat place, with great professionals. 100% recommend.
Helpful Review