✓ Last verified: March 19, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff

Known For: Pain management practice in Portland, Maine offering IV ketamine infusions specifically for chronic pain conditions, led by an interventional pain specialist.
| Google Reviews | 4.8 ⭐ (30+ reviews) |
| Location | Portland, Maine |
| Address | 1945 Congress Street, Building C, Suite 103, Portland, ME 04102 |
| Phone | (207) 835-8116 |
| Website | portlandpainsolutions.com |
| Treatments | IV Ketamine Infusions, Interventional Pain Management, Nerve Blocks |
| Conditions | Chronic Pain, CRPS, Neuropathy, Fibromyalgia, Depression, Anxiety |
| Cost | Contact for pricing |
| Insurance | Insurance accepted for pain management; ketamine may be self-pay |
| KAP Available | No – IV infusion model focused on pain |
| Clinical Lead | Interventional pain specialist |
HealingMaps Take: Portland Pain Solutions is particularly well-suited for chronic pain patients in southern Maine seeking ketamine therapy. Their interventional pain management background means patients get ketamine as part of a comprehensive pain treatment strategy rather than as a standalone service. A solid option for those whose primary driver is pain rather than mood disorders.
Market Position: Portland Pain Solutions is an IV-ketamine-focused clinic in the Portland metro — the most common cash-pay protocol in the HealingMaps verified directory.
Industry pricing reference. Portland Pain Solutions has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.
| Protocol | Typical Industry Cost | Offered Here |
|---|---|---|
| IV Ketamine | $350–$650/session | ✓ Yes |
| Spravato (esketamine) | $0–$250 copay (insured) | — |
| IM Ketamine | $250–$400/injection | — |
| KAP (with therapist) | $400–$1,200/session | — |
| At-home troches | $150–$300/month | — |
Sources: CDC PLACES 2023 (Cumberland County, ME, crude prevalence) · U.S. Census ACS 5 Year · HealingMaps proprietary patient inquiry data.
Behind this data: HealingMaps has analyzed 23,496 patient inquiries (Oct 2022 – Mar 2026), mapped 1,473 verified clinics across 3,142 counties, scraped 132 clinic pricing pages, and collected 658 practitioner survey responses. This snapshot reflects our multi-source methodology.
Treatment-resistant depression — typically defined as failure on two or more antidepressant trials — is the FDA-approved indication for Spravato and the most common clinical qualifier for ketamine therapy insurance coverage. Source: HealingMaps 2026 Ketamine Clinic Intelligence Report — drawn from 23,496 patient inquiries and 132 clinic website analyses.
This 3-question summary is matched to the protocols and conditions Portland Pain Solutions treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.
Portland Pain Solutions treats depression via IV ketamine (off-label, evidence-based). Insurance coverage is rare for IV/KAP — most patients pay out of pocket. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.
Yes — Portland Pain Solutions treats chronic pain. They use IV ketamine for pain, which typically means longer infusion times and higher cumulative doses than mental-health protocols. Common indications include complex regional pain syndrome (CRPS), fibromyalgia, and certain neuropathic pain syndromes. Pain pricing varies significantly by structure: per-infusion vs. multi-day inpatient packages — verify how this clinic structures their billing.
Yes — Portland Pain Solutions treats anxiety, including generalized anxiety, social anxiety, and panic disorder. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines. Worth asking which of their protocols they typically recommend for anxiety-primary patients.
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