Southern Colorado TMS & Ketamine – Pueblo, Colorado Ketamine Clinics

✓ Last verified: January 18, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff

Known For: Southern Colorado’s most established ketamine and TMS center, operating since 2011 — one of the earliest ketamine clinics in the state. Offers IV ketamine, Spravato, and TMS for comprehensive treatment-resistant depression care in the Pueblo region.

HealingMaps Take: Southern Colorado TMS & Ketamine is a quiet powerhouse that most people outside Pueblo do not know about. Operating since 2011, this is one of the oldest ketamine clinics in Colorado — predating the Spravato FDA approval by nearly a decade and the ketamine therapy boom by even longer. That longevity matters: the clinical team has administered thousands of infusions and has the kind of pattern recognition that newer clinics simply cannot match. The triple-modality model (IV ketamine + Spravato + TMS) means the practice can match treatment to patient needs and insurance status. Spravato and TMS are covered by most insurance plans, giving patients two FDA-approved entry points; IV ketamine is available for patients who need higher bioavailability or faster onset. For the 170,000+ residents of the Pueblo metro and the broader southern Colorado region — including Trinidad, Walsenburg, La Junta, and Canon City — this is the only advanced depression treatment center that does not require a 90-minute drive to Colorado Springs or two hours to Denver. In a region with some of the highest depression and suicide rates in Colorado, that access matters.

Market Position: Southern Colorado TMS & Ketamine is a Spravato-certified clinic in the Pueblo metro. Spravato (esketamine) is the FDA-approved ketamine treatment that most commercial insurance plans cover after prior authorization — unlike cash-pay IV ketamine.

Ketamine Protocols Compared — What’s Offered at Southern Colorado TMS & Ketamine

Industry pricing reference. Southern Colorado TMS & Ketamine has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.

What to Expect at Your First Southern Colorado TMS & Ketamine Appointment

1. Initial intake call — Insurance verification, prior authorization workflow (Spravato requires documentation of failure on at least two antidepressant trials), and clinical eligibility check. Call (719) 496-4366 to schedule.
2. Medical evaluation — in-person or telehealth psychiatric assessment, vitals check, and review of current medications with the Southern Colorado TMS & Ketamine clinical team.
3. First treatment session — supervised IV ketamine infusion in a private treatment room, lasting approximately 60–90 minutes (40-minute infusion + recovery). Sessions are held at 27 Montebello Rd, Suite 200, Pueblo, CO 81001. You’ll have a comfortable chair or recliner, dim lighting, and direct medical monitoring throughout.
4. Recovery and follow-up — observation period after dosing, mood check-in with the clinical team, and scheduling your next session. Arrange for a ride home; do not drive for 24 hours after your IV session.

What to Ask on Your Southern Colorado TMS & Ketamine Consult Call

• How long has the Southern Colorado TMS & Ketamine clinical team been delivering ketamine therapy, and what specialty training do your providers hold?
• Walk me through Southern Colorado TMS & Ketamine’s Spravato prior authorization process versus your IV ketamine cash-pay or superbill workflow — which is the better fit for my insurance situation?
• Colorado’s Natural Medicine Health Act covers certain psychedelics — how does your ketamine practice integrate with broader psychedelic-therapy options patients may consider?
• What does Southern Colorado TMS & Ketamine recommend for patients who don’t respond to the standard 6-session acute series?

Pueblo Ketamine Market Snapshot

Sources: CDC PLACES 2023 (Pueblo County, CO, crude prevalence) · U.S. Census ACS 5 Year · HealingMaps proprietary patient inquiry data.

• Adult depression in Pueblo County, CO: 22.6%
• Frequent mental distress (14+ days per month): 17.3%
• Adults lacking health insurance: 16.3%
• Pueblo County population: 168,135 · median household income $59,436
• Recent Pueblo-area inquiries to HealingMaps: A growing stream of Colorado residents have recently contacted us seeking ketamine care

Behind this data: HealingMaps has analyzed 23,496 patient inquiries (Oct 2022 – Mar 2026), mapped 1,473 verified clinics across 3,142 counties, scraped 132 clinic pricing pages, and collected 658 practitioner survey responses. This snapshot reflects our multi-source methodology.

From the 2026 Ketamine Industry Report

The majority of ketamine patients moving from acute to maintenance phase report monthly maintenance sessions as the typical long-term cadence — balancing clinical efficacy with affordability. Source: HealingMaps 2026 Ketamine Clinic Intelligence Report — drawn from 23,496 patient inquiries and 132 clinic website analyses.

Patient Questions about Southern Colorado TMS & Ketamine

This 6-question summary is matched to the protocols and conditions Southern Colorado TMS & Ketamine treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.

What ketamine protocols does Southern Colorado TMS & Ketamine offer?

Southern Colorado TMS & Ketamine offers Spravato and IV ketamine — a 2-protocol practice. Patients can switch between or combine modalities without changing providers. Confirm specific dosing schedules and which protocols are recommended for your condition during your consult.

Does Southern Colorado TMS & Ketamine offer Spravato (esketamine)?

Yes — Southern Colorado TMS & Ketamine offers Spravato, which means they’re FDA REMS-certified and maintain the required two-hour in-office monitoring window after each dose. Spravato is the primary insurance-covered ketamine option for treatment-resistant depression. Worth confirming the prior-authorization timeline before booking your first session.

Is Southern Colorado TMS & Ketamine suited for treatment-resistant depression?

Southern Colorado TMS & Ketamine treats depression via Spravato (FDA-approved for TRD), and IV ketamine (off-label, evidence-based). The Spravato pathway is the most likely to obtain commercial insurance coverage. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.

Does Southern Colorado TMS & Ketamine treat chronic pain conditions?

Yes — Southern Colorado TMS & Ketamine treats chronic pain. They use IV ketamine for pain, which typically means longer infusion times and higher cumulative doses than mental-health protocols. Common indications include complex regional pain syndrome (CRPS), fibromyalgia, and certain neuropathic pain syndromes. Pain pricing varies significantly by structure: per-infusion vs. multi-day inpatient packages — verify how this clinic structures their billing.

Does Southern Colorado TMS & Ketamine treat PTSD?

Yes — Southern Colorado TMS & Ketamine treats PTSD. Both Spravato and IV ketamine can be used for trauma. Ketamine for trauma differs from depression treatment: dosing is often lower per session, and pairing the protocol with trauma-focused therapy between sessions is common. A reasonable consult question: whether PTSD patients here typically use ketamine alone or alongside an outside therapist.

Can Southern Colorado TMS & Ketamine help with anxiety disorders?

Yes — Southern Colorado TMS & Ketamine treats anxiety, including generalized anxiety, social anxiety, and panic disorder. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines. Worth asking which of their protocols they typically recommend for anxiety-primary patients.

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