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Natural Supplements To Help Support Psychedelic Therapy

Natural Supplements To Help Support Psychedelic Therapy

OK, so you’re giving psychedelic therapy a go, congratulations on taking the leap. Before diving in, though, there’s a lot of prep necessary, and things to do to prepare your mind and body. From which ones to choose and what type of treatment works best, to potential psychedelics side effects and downtime. And that’s only a few things worth noting.

But did you know there are natural supplements that not only support psychedelic therapy, but also help deal with the side effects? Seriously. Plus, some of these help with potential anxiety over whether or not therapy will work.

So what natural supplements could be helpful before trying psychedelics therapy? Below are five to consider.

RELATED: What Is LSA? Your Guide To The Complicated Psychedelic

Lion’s Mane

Lion’s mane mushroom (Hericium erinaceus) is an edible mushroom in the tooth fungus group. This guide explains its medicinal use and benefits
Lion’s Mane Mushroom // Image via iStock

One of the most powerful medicinal mushrooms, the lion’s mane mushroom is a gorgeous looking big ball of white fluff that got worldwide attention for its incredible impact on brain health and the effect on the overall nervous system.

Containing not one, but two nerve growth factors (hericenones and erinacines), lion’s mane stimulates regeneration and remyelination (by producing more myelin – a compound which coats and protects our nerves) of the nerves. This makes it a promising tool against Alzheimer’s, Parkinson’s, MS, nerve damage, anxiety and depression.

Studies show its incredible impact on dealing with anxiety and depression, which is one of the main reasons why lion’s mane is so important when it comes to psychedelic therapy. Some even suggest combining it with psilocybin and niacin or vitamin B3 to “allow your brain to make new connections, get a healthier brain and mentally ‘clean up’ yourself.”

It’s easy to find in most drugstores in the form of a pill, but also comes as a powder to add to smoothies, adaptogenic drinks, coffee, and even bone broth. Specialty stores or the farmer’s market are often good places to purchase.

Also Read: Why has growing mushrooms at home suddenly started to boom?

Cod Liver Oil

Cod liver oil can be a natural supplement that is used with psychedelic therapy
Cod Liver Oil // Image via Pixabay

Known for centuries and used to help treat rheumatism, aching joints, and stiff muscles, as well as protect from the cold, cod liver oil is rich in vitamins A, D, and omega-3 fatty acids. This makes it an amazing natural supplement that can be a great daily addition to anyone’s diet.

Cod liver oil has been linked with decreasing anxiety and depression. This makes it a perfect ally combat mental health issues often associated with psychedelic therapy. When taken in conjunction with a psychedelic, it can potentially have a greater impact and give you better results. It is available in both pill form or even in pure oil.

Green Tea

Green tea can be a natural supplement that is used with psychedelic therapy
Green Tea // Image via Pixabay

Loaded with antioxidants, green tea helps fight free radicals, lowers overall inflammation, and protects against oxidative damage. It also contains high levels of caffeine and L-theanine, both of which stimulate dopamine. These also increase the activity of the inhibitory neurotransmitter GABA, which has anti-anxiety effects.

When combined together, caffeine and L-theanine have powerful effects in improving brain function, and are therefore amazing additions to psychedelic therapy, nourishing the brain while in treatment.

When choosing green tea, look for the source and always try to get loose leaf versions. This helps avoid any unnecessary additives and potential toxins. Additionally, it is available in pill form — which is better for larger doses.

Vitamin D

Vitamin D can be a natural supplement that is used with psychedelic therapy
Vitamin D // Image via Pexels

Also called the “sun vitamin”, vitamin D is a fat-soluble vitamin which is typically obtained from the sun’s UV rays. This triggers vitamin D synthesis to penetrate the skin’s barrier. It’s also present in some foods, but in very small quantities which are hard to absorb by our bodies.

Due to indoor lifestyles and changing seasons, more people are becoming deficient in vitamin D. That’s why so many recommend some sort of natural supplement. The actual dosage that an individual needs can be tested through specific vitamin D tests. These are often available over-the-counter.

Vitamin D promotes calcium absorption in the gut and it’s crucial for bone growth and bone remodeling. Without sufficient vitamin D, bones can become thin, brittle, or misshapen. It also reduces inflammation as well as promotes cell growth, improves neuromuscular and immune function, and helps manage glucose metabolism.

Since deficiency can lead to depression and anxiety, adding it to your psychedelic treatment can help you go through the session with ease and support potential side effects.

It often comes as a supplement in pill form, and uses IU (international units) for measurement. The number of IUs one needs comes after taking the vitamin D deficiency test.


A probiotic can be a natural supplement that is used with psychedelic therapy
Probiotics // Image via Pexels

Probiotics are extremely important supplements. They help nourish the gut flora and feed microbiome by replenishing it with good bacteria, eliminating the bad bacteria.

They usually contain high doses of Lactobacillus and Bifidobacterium strains, the most common bacteria which reside in our gut. These all may have a different impact on the body. While some may help absorb or digest a certain food, others coat the gut lining or prevent from a specific illness. That’s why all probiotic supplements contain many different strains which when working together yield the best results.

Many consider the gut to be a “second brain”, with the connection to our actual brain much stronger than we think. It nourishes it with healthy microorganisms and keeps it thriving for our mental health. This is especially true for levels of dopamine and serotonin.

Since it improves brain function and helps with anxiety or depression, it may be helpful to try with psychedelic therapy. That’s why taking them regularly while attending sessions may bring added benefits in the long run.

If giving psychedelic therapy a go, get all the tools available to support the journey along the way. The five natural supplements above are easy to encounter, easy to take, and may lead to a better psychedelic experience.

RELATED: Reishi Mushroom (Ganoderma Lucidum)

Karla Tafra

View all posts by Karla Tafra

Karla is a freelance writer, yoga teacher and nutritionist who's been writing about nutrition, fitness, yoga, mindfulness, and overall health and wellness topics for over seven years. She's written for numerous publications such as Healthline, Livesavvy,, Well + Good, and many others, sharing her love of storytelling and educating. She loves talking about superfoods and another amazing plant powers that people can benefit from if they learn how to use it properly. Her passion lies in helping others not only eat healthier meals but implement good eating habits, find a great relationship with food & achieve a balanced lifestyle. She believes that the only diet and lifestyle that's worth creating is the one you can stick to, so she aims to find what that means for each and every individual. Teaching WHY we eat, and not only WHAT we eat, is the premise of her approach.

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