HealingMaps Take: Lux Skin carries the strongest review profile in the Philadelphia metro at 4.9 stars from 234 reviews. Transparent GLP-1 pricing (semaglutide from $500, tirzepatide from $600) removes guesswork. The MD-supervised program with two Main Line locations (King of Prussia and Bryn Mawr) serves the region’s most affluent corridor. The focus is specifically GLP-1 weight loss peptides.
Lux Skin & Lasers offers 4 specific peptide compounds (BPC-157, Semaglutide, Tirzepatide, and Retatrutide), placing it in the top half of the 10+ Pennsylvania peptide clinics in our directory (the median clinic menu offers 3 compounds; the deepest offers 14). The clinic is physician-led (MD or DO); about a third of Pennsylvania peptide clinics in our directory are.
✓ Last verified: March 17, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff
| Review Scores | Birdeye: 4.9 (234 reviews) |
| Location | King of Prussia, Pennsylvania |
| Address | 731 W Dekalb Pike, King of Prussia, PA 19406 |
| Phone | (484) 322-5316 |
| Website | luxskinlasers.com |
| Treatments | Semaglutide, Tirzepatide, Retatrutide |
| Conditions Treated | Weight loss, metabolic optimization, body composition |
| Administration | Weekly subcutaneous injection |
| Cost | Semaglutide intro $500 (4-week); then $500–$600/month. Tirzepatide $600–$700/month |
| Insurance | Cash pay |
| Clinical Lead | John J.W. Lee, M.D. (plastic/oculofacial surgeon); Dr. Castelli (weight loss program) |
Your prescribing provider, Dr. Jack Lee, is verified in the federal CMS National Plan & Provider Enumeration System (NPPES) under NPI 1538653217, with a primary specialty of Dermatology, MOHS-Micrographic Surgery and a primary practice address in Newtown, PA. CMS records show this NPI has been active since 2018. NPPES record verified 2026-05-08. Dr. Jack Lee’s NPI tenure is the longest-tenured among the 5 Pennsylvania peptide providers we’ve verified in NPPES (longest-tenured peer registered in 2005; cohort median 2006).
What this means for you: In the US, any actively state-licensed physician can legally prescribe compounded peptides — board certification in a specific specialty isn’t required for peptide prescriptions. Dermatology training covers skin and aesthetic indications; GHK-Cu and other tissue-repair peptides are common in dermatology-led peptide menus.
National peptide therapy pricing — based on 487 verified peptide clinics in our directory (April 2026 data). Pricing for 2 compounds below is pre-loaded from this listing’s published rates; other compounds use HealingMaps directory medians. Adjust the calculator below to model your own protocol.
Most Lux Skin & Lasers patients report the consult-to-first-injection window runs 1–3 weeks depending on lab turnaround and pharmacy fulfillment.
The questions below are pulled from the gaps in this specific listing — areas the clinic doesn’t publicly answer that you should clarify before booking. Each one is designed to get you a useful answer in 30 seconds or less.
“The pricing transparency at Lux was refreshing. I knew exactly what semaglutide would cost before my first visit. The results have been incredible. — Google Review”
Lux Skin and Lasers is a medical spa with locations in King of Prussia and Bryn Mawr on Philadelphia’s Main Line. Dr. John J.W. Lee, a plastic surgeon, leads the practice. Dr. Castelli oversees the weight loss peptide program offering semaglutide, tirzepatide, and retatrutide. Transparent pricing starts at $500 for a 4-week semaglutide introductory package.
For more on how peptide therapy works, see our guide to peptide therapy.
234 reviews at 4.9 stars is the best review profile in the market. Transparent pricing is a major differentiator. Two Main Line locations add convenience.
The peptide menu is limited to GLP-1 weight loss compounds. Patients seeking BPC-157, growth hormone peptides, or other compounds will need another provider.
Call or book online at either location. Semaglutide starts at $500 for a 4-week introductory package.
Explore more vetted peptide therapy clinics near you in our nationwide directory.
Looking for more BPC-157 providers? Browse our directory of BPC-157 and recovery peptide clinics — including options in Pennsylvania across the United States.
Based on this listing, Lux Skin & Lasers names 4 specific peptide compounds: BPC-157, Semaglutide, Tirzepatide, and Retatrutide. The clinic may offer additional compounds not published on its public listing — confirm the full menu on a consult call.
Yes. Dr. Jack Lee is registered in the federal CMS National Plan & Provider Enumeration System (NPPES) under NPI 1538653217, with a primary specialty of Dermatology, MOHS-Micrographic Surgery and a primary practice address in Newtown, PA. The NPI has been active since 2018.
Lux Skin & Lasers doesn’t mention telehealth or virtual visits on its listing. Most peptide clinics require in-person evaluation for the initial consult; some offer virtual follow-ups once a patient is stable. If geography or travel matters to you, ask on the consult call whether they can prescribe and follow up virtually — and which states they’re licensed to do so in.
Among verified Pennsylvania peptide clinics in the HealingMaps directory, Lux Skin & Lasers ranks in the top half of Pennsylvania peptide clinics in the directory by compound depth. Compound depth is one signal among several — provider credentials, pharmacy sourcing transparency, and lab requirements also matter when comparing.
Lux Skin & Lasers is located in King of Prussia, Pennsylvania. The full street address, phone number, and hours are listed in the data card above.
Themes drawn from HealingMaps editorial analysis of verified Pennsylvania peptide clinics in our directory. Refreshed quarterly; percentages rounded to nearest 5%.
Across Pennsylvania peptide clinics in our directory, Sermorelin appears in 55% of listings; BPC-157 in 45%; CJC-1295 in 40%; Ipamorelin in 40%. Compounds appearing in fewer than 20% of Pennsylvania listings — including Tesamorelin, GHK-Cu, TB-500 — are less commonly disclosed; patients seeking those should specifically ask whether the clinic prescribes them.
5% of Pennsylvania clinics in our directory openly state whether they use a 503A or 503B compounding pharmacy. The rest leave the class unstated. The distinction matters for patients — 503A pharmacies fill prescriptions individually after your provider writes them (typically a few-day wait, in-state shipping), while 503B outsourcing facilities pre-batch under direct FDA inspection (often supporting same-visit fulfillment and direct-to-home shipping). Worth asking specifically before you book.
40% of verified Pennsylvania clinics name an MD or DO as clinical lead (this listing’s clinical lead is Dermatology, MOHS-Micrographic Surgery-trained). The remainder are NP/PA-led or don’t publicly name a specific prescribing clinician. Any state-licensed physician, NP, or PA can legitimately prescribe compounded peptides — but knowing your prescriber’s training and tenure helps you assess fit for your specific protocol.
The median Pennsylvania clinic in our directory publishes 3 specific peptide compounds on its listing. The deepest disclosed menu names 14; 25% of listings name no specific compounds at all. A wide menu means more options at one clinic; a narrow menu can reflect specialization (e.g. weight-loss-only programs) or limited public disclosure (the clinic prescribes more than it advertises).
Pharmacy sourcing: This clinic doesn’t state its 503A or 503B compounding pharmacy partner. The class affects how your prescription is fulfilled — custom-compounded with in-state shipping (503A) versus pre-batched with broader shipping including direct-to-home delivery (503B) — so it’s worth asking before starting any compounded protocol.
Lux Skin & Lasers’s named prescriber is verifiable in the CMS National Plan & Provider Enumeration System — the highest single trust signal we look for. The clinic names 4 specific peptide compounds — including BPC-157, Semaglutide, and Tirzepatide. What’s not publicly stated: which pharmacy class (503A vs 503B) handles compounding. Worth asking on your consult call. See our full vetting rubric →
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